Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 13/20 | 0.50 |
| ▸ | PAK3 | O75914 | 1/20 | 0.45 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.45 |
| ▸ | PAK2 | Q13177 | 1/20 | 0.45 |
| ▸ | UBE2M | P61081 | 3/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12004739 | 0.93 | CXCR3 (0.55) | CXCR3EPHX2PAK3PAK1PAK2 | |
| SCHEMBL6863633 | 0.93 | CXCR3 (0.55) | CXCR3EPHX2PAK3PAK1PAK2 | |
| SCHEMBL6864238 | 0.93 | CXCR3 (0.55) | CXCR3EPHX2PAK3PAK1PAK2 | |
| SCHEMBL6863225 | 0.90 | EPHX2 (0.47) | EPHX2MEN1KMT2A | |
| SCHEMBL6863176 | 0.83 | S1PR2 (0.40) | CXCR3 | |
| SCHEMBL6863181 | 0.81 | S1PR2 (0.41) | — | |
| SCHEMBL25993053 | 0.80 | EPHX2 (0.67) | CXCR3EPHX2 | |
| SCHEMBL12005295 | 0.79 | CXCR3 (0.46) | CXCR3EPHX2PAK3PAK1PAK2 | |
| SCHEMBL12005297 | 0.79 | CXCR3 (0.46) | CXCR3EPHX2PAK3PAK1PAK2 | |
| SCHEMBL12005445 | 0.79 | CXCR3 (0.46) | CXCR3EPHX2PAK3PAK1PAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032291-A1 | SELECTIVE CALCIUM CHANNEL MODULATORS | ZALICUS PHARMACEUTICALS LTD . (CA) | 2011-03-24 | — | — | WO | disclosed |