Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863248 | 0.90 | CXCR3 (0.51) | EPHX2KMT2AMEN1 | |
| SCHEMBL12004739 | 0.84 | CXCR3 (0.55) | EPHX2 | |
| SCHEMBL6863633 | 0.84 | CXCR3 (0.55) | EPHX2 | |
| SCHEMBL6864238 | 0.84 | CXCR3 (0.55) | EPHX2 | |
| SCHEMBL6863253 | 0.80 | CCR3 (0.38) | NPC1RAB9AMAPTKMT2APOLB | |
| SCHEMBL2753005 | 0.78 | RAB9A (0.70) | EPHX2NPC1RAB9ATSHREPHX1 | |
| SCHEMBL11431700 | 0.75 | RAB9A (0.60) | EPHX2NPC1RAB9ATSHREPHX1 | |
| SCHEMBL10327137 | 0.74 | LMNA (0.59) | POLB | |
| SCHEMBL10326796 | 0.74 | LMNA (0.59) | POLB | |
| SCHEMBL10106568 | 0.74 | LMNA (0.59) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032291-A1 | SELECTIVE CALCIUM CHANNEL MODULATORS | ZALICUS PHARMACEUTICALS LTD . (CA) | 2011-03-24 | — | — | WO | disclosed |