Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 7/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | WNT3 | P56703 | 2/20 | 0.34 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863109 | 0.94 | S1PR2 (0.41) | S1PR2P2RX7ALDH1A1WNT3SFRP1 | |
| SCHEMBL6863044 | 0.94 | S1PR2 (0.41) | S1PR2P2RX7ALDH1A1WNT3SFRP1 | |
| SCHEMBL12005722 | 0.94 | S1PR2 (0.41) | S1PR2P2RX7ALDH1A1WNT3SFRP1 | |
| SCHEMBL6863176 | 0.90 | S1PR2 (0.40) | S1PR2TACR1 | |
| SCHEMBL12015159 | 0.85 | ALDH1A1 (0.40) | S1PR2P2RX7ALDH1A1WNT3SFRP1 | |
| SCHEMBL12015288 | 0.85 | ALDH1A1 (0.40) | S1PR2P2RX7ALDH1A1WNT3SFRP1 | |
| SCHEMBL6863132 | 0.83 | S1PR2 (0.40) | S1PR2P2RX7 | |
| SCHEMBL6863244 | 0.83 | S1PR2 (0.40) | S1PR2P2RX7 | |
| SCHEMBL6863248 | 0.81 | CXCR3 (0.51) | — | |
| SCHEMBL6863253 | 0.79 | CCR3 (0.38) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032291-A1 | SELECTIVE CALCIUM CHANNEL MODULATORS | ZALICUS PHARMACEUTICALS LTD . (CA) | 2011-03-24 | — | — | WO | disclosed |