SCHEMBL6863625

SCHEMBL6863625

CCCCCCCCCCC(CCCCCCCCCC)(C(=O)OCC(C)(C)C)C(CCCCCCCCCC)(CCCCCCCCCC)C(=O)OCC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.43
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40
GGPS1 O95749 5/20 0.37
NAAA Q02083 1/20 0.37
DGKA P23743 1/20 0.37
SMPD1 P17405 1/20 0.37
FDPS P14324 7/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1837065 0.84 LMNA (0.44) MEN1KMT2ACYP4F2CYP4A11
SCHEMBL6871664 0.82 MEN1 (0.59) CES2MEN1MAPTKMT2AATM
SCHEMBL6863717 0.81 NAAA (0.48) CES2MEN1MAPTKMT2AATM
SCHEMBL28713995 0.77 CYP4F2 (0.50) CES2MEN1MAPTKMT2AATM
SCHEMBL6870963 0.76 MAPT (0.42) CES2MEN1MAPTKMT2AATM
SCHEMBL6873197 0.76 MEN1 (0.57) CES2MEN1MAPTKMT2AATM
SCHEMBL6873127 0.76 MEN1 (0.47) CES2MEN1MAPTKMT2AATM
SCHEMBL2461067 0.76 CYP4F2 (0.43) CES2MEN1MAPTKMT2AATM
SCHEMBL1784700 0.76 KMT2A (0.35) KMT2ACYP4F2CYP4A11
SCHEMBL6753228 0.75 NAAA (0.47) MEN1MAPTKMT2AATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1165633-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SPA (IT) 2004-07-14 EP claimed
US-6716939-B2 COMPRISING TITANIUM, MAGNESIUM, HALOGEN AND AN ELECTRON DONOR COMPOUND SELECTED FROM ESTERS OF SUBSTITUTED SUCCINIC ACIDS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-04-06 US claimed
US-20020183575-A1 Components and catalysts for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2002-12-05 US claimed
EP-1165633-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2002-01-02 EP claimed
WO-2001057099-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-08-09 WO claimed
EP-1165633-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SPA (IT) 2004-07-14 EP disclosed
US-6716939-B2 COMPRISING TITANIUM, MAGNESIUM, HALOGEN AND AN ELECTRON DONOR COMPOUND SELECTED FROM ESTERS OF SUBSTITUTED SUCCINIC ACIDS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-04-06 US disclosed
US-20020183575-A1 Components and catalysts for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2002-12-05 US disclosed
EP-1165633-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2002-01-02 EP disclosed
WO-2001057099-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-08-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183575-A1 Components and catalysts for the polymerization of olefins SCO2, ECI1, MT-CO2 CES2 2121/4885MEN1 4525/4885MAPT 2834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.