Levacetylleucine

Levacetylleucine

SCHEMBL6863674

CC(=O)N[C@H](CC(C)C)C(=O)O.C[C@@H](N)C(=O)O

nearest known ligand 0.85

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.85
MEN1 O00255 1/20 0.56
LMNA P02545 1/20 0.56
KMT2A Q03164 1/20 0.56
LAP3 P28838 3/20 0.56
MAPT P10636 2/20 0.53
KDM4E B2RXH2 1/20 0.52
THRB P10828 1/20 0.52
ALOX15 P16050 1/20 0.52
NFKB1 P19838 1/20 0.52
PTGS2 P35354 1/20 0.52
THPO P40225 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
FOLH1 Q04609 5/20 0.50
LTA4H P09960 1/20 0.50
SLC7A5 Q01650 1/20 0.47
NAALAD2 Q9Y3Q0 2/20 0.46
PLA2G2A P14555 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Levacetylleucine SCHEMBL714003 0.92 ALDH1A1 (1.00) ALDH1A1MEN1LMNAKMT2ALAP3
Levacetylleucine SCHEMBL9438432 0.92 ALDH1A1 (1.00) ALDH1A1MEN1LMNAKMT2ALAP3
Acetylleucine SCHEMBL282371 0.92 ALDH1A1 (1.00) ALDH1A1MEN1LMNAKMT2ALAP3
Levacetylleucine SCHEMBL282372 0.92 ALDH1A1 (1.00) ALDH1A1MEN1LMNAKMT2ALAP3
Levacetylleucine SCHEMBL18954336 0.90 ALDH1A1 (0.96) ALDH1A1MEN1LMNAKMT2ALAP3
Levacetylleucine SCHEMBL5532016 0.90 ALDH1A1 (0.96) ALDH1A1MEN1LMNAKMT2ALAP3
Levacetylleucine SCHEMBL5527234 0.90 ALDH1A1 (0.96) ALDH1A1MEN1LMNAKMT2ALAP3
Levacetylleucine SCHEMBL7923132 0.90 ALDH1A1 (0.96) ALDH1A1MEN1LMNAKMT2ALAP3
Acetylleucine SCHEMBL49287 0.89 ALDH1A1 (0.79) ALDH1A1MEN1LMNAKMT2ALAP3
Acetylleucine SCHEMBL27683922 0.89 ALDH1A1 (0.79) ALDH1A1MEN1LMNAKMT2ALAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6800608-B2 PREPARATION OF STABILIZED GLYCOPEPTIDE ANTIBIOTIC CONJUGATE; FORM GLYCOPEPTIDE ANTIBIOTIC, MIX WITH STABILIZING AGENT THAT PREVENTS DIMERIZATION, HEAT, STORE IN DILUENT BUFFER BECKMAN COULTER, INC. 2004-10-05 US disclosed
US-20030077670-A1 Homogeneous assay of vancomycin using a stable particle-vancomycin conjugate, a novel rate enhancer, and a novel dose response modulator BECKMAN COULTER, INC. 2003-04-24 US disclosed