Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | ELANE | P08246 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019802 | 0.81 | TSHR (0.54) | TDP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8687175 | 0.79 | PTGER4 (0.52) | KDM4EALDH1A1ELANEMEN1KMT2A | |
| SCHEMBL8689676 | 0.79 | ALDH1A1 (0.56) | KDM4EALDH1A1ELANEKMT2ARXFP1 | |
| SCHEMBL8688955 | 0.75 | CCR2 (0.59) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5356066 | 0.73 | TDP1 (0.46) | TDP1KDM4EALDH1A1ELANEMEN1 | |
| SCHEMBL11730958 | 0.73 | ALDH1A1 (0.51) | KDM4EALDH1A1ELANEKMT2ASMN1; SMN2 | |
| SCHEMBL5623862 | 0.72 | F10 (0.57) | TDP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1392918 | 0.72 | NOD2 (0.64) | TDP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL30585515 | 0.72 | NOD2 (0.64) | TDP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL20139846 | 0.71 | FOLH1 (0.47) | TDP1KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800627-B1 | CENTRAL NERVOUS SYSTEM, CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS, DIABETES INSPIDUS, SLEEP APNEA | VERNALIS RESEARCH LIMITED (GB) | 2004-10-05 | — | — | US | disclosed |