Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 17/20 | 0.64 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864528 | 0.91 | GPR52 (0.55) | GPR52NPC1RAB9A | |
| SCHEMBL6864177 | 0.89 | GPR52 (0.51) | GPR52PTGER4NPC1RAB9A | |
| SCHEMBL13505881 | 0.87 | GPR52 (0.49) | GPR52PTGER4 | |
| SCHEMBL6865232 | 0.86 | GPR52 (0.48) | GPR52PTGER4 | |
| SCHEMBL13506435 | 0.84 | PDE4B (0.48) | GPR52 | |
| SCHEMBL13505604 | 0.83 | GPR52 (0.45) | GPR52NPC1RAB9A | |
| SCHEMBL6864796 | 0.81 | GPR52 (0.77) | GPR52HTR2B | |
| SCHEMBL6864979 | 0.80 | GPR52 (0.69) | GPR52HTR2B | |
| SCHEMBL6864264 | 0.78 | GPR52 (0.67) | GPR52 | |
| SCHEMBL6864495 | 0.78 | GPR52 (1.00) | GPR52HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |