Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 18/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863891 | 0.91 | GPR52 (0.64) | GPR52NPC1RAB9A | |
| SCHEMBL13505604 | 0.89 | GPR52 (0.45) | GPR52NPC1RAB9A | |
| SCHEMBL13506119 | 0.88 | GPR52 (0.40) | GPR52TACR1 | |
| SCHEMBL6865532 | 0.87 | GPR52 (0.40) | GPR52TACR1 | |
| SCHEMBL13506389 | 0.85 | PDE4B (0.46) | GPR52 | |
| SCHEMBL6864177 | 0.81 | GPR52 (0.51) | GPR52NPC1RAB9A | |
| SCHEMBL13505881 | 0.78 | GPR52 (0.49) | GPR52 | |
| SCHEMBL6865232 | 0.77 | GPR52 (0.48) | GPR52 | |
| SCHEMBL13506622 | 0.75 | LMNA (0.46) | — | |
| SCHEMBL13506435 | 0.75 | PDE4B (0.48) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |