SCHEMBL6863985

SCHEMBL6863985

NCC(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 2/20 0.47
PTGS1 P23219 1/20 0.47
GSTK1 Q9Y2Q3 1/20 0.47
FOLH1 Q04609 2/20 0.38
RIMKLA Q8IXN7 1/20 0.38
NAALAD2 Q9Y3Q0 1/20 0.38
BMP1 P13497 2/20 0.36
CCKBR P32239 1/20 0.35
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
PTGS2 P35354 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
DPP4 P27487 1/20 0.34
DPP8 Q6V1X1 1/20 0.34
DPP9 Q86TI2 1/20 0.34
GNPAT O15228 1/20 0.34
TERT O14746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6863991 1.00 GLO1 (0.47) GLO1PTGS1GSTK1FOLH1RIMKLA
SCHEMBL29350792 0.98 GLO1 (0.48) GLO1PTGS1GSTK1FOLH1RIMKLA
SCHEMBL22111148 0.94 GLO1 (0.49) GLO1PTGS1GSTK1FOLH1RIMKLA
SCHEMBL32670748 0.94 GLO1 (0.49) GLO1PTGS1GSTK1FOLH1RIMKLA
SCHEMBL6863995 0.92 GLO1 (0.45) GLO1PTGS1GSTK1BMP1ALDH1A1
SCHEMBL29050824 0.91 PTGS1 (0.51) GLO1PTGS1GSTK1FOLH1RIMKLA
SCHEMBL2804509 0.91 PTGS1 (0.51) GLO1PTGS1GSTK1FOLH1RIMKLA
SCHEMBL30631707 0.88 PTGS1 (0.43) GLO1PTGS1GSTK1ALDH1A1LMNA
SCHEMBL22892433 0.87 GLO1 (0.43) GLO1PTGS1GSTK1ALDH1A1LMNA
SCHEMBL30261857 0.87 FOLH1 (0.47) GLO1FOLH1RIMKLANAALAD2BMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228958-A1 TSP1 INHIBITOR DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-07-17 US claimed
EP-4467561-A1 TSP1 INHIBITOR Daiichi Sankyo Company, Limited (JP) 2024-11-27 EP claimed
WO-2023136342-A1 TSP1 INHIBITOR 第一三共株式会社 2023-07-20 WO claimed
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
US-12514939-B2 Stable radiopharmaceutical compositions and uses thereof ALPHA-9 ONCOLOGY, INC. (CA) 2026-01-06 US disclosed
US-20250255993-A1 STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND USES THEREOF ALPHA-9 ONCOLOGY INC. (CA) 2025-08-14 US disclosed
US-20250228958-A1 TSP1 INHIBITOR DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-07-17 US disclosed
EP-4467561-A1 TSP1 INHIBITOR Daiichi Sankyo Company, Limited (JP) 2024-11-27 EP disclosed
WO-2023136342-A1 TSP1 INHIBITOR 第一三共株式会社 2023-07-20 WO disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed
US-6799121-B2 AUTOMATIC PROCESS YORK UNIVERSITY (CA) 2004-09-28 US disclosed
US-20020001814-A1 Sequencing of peptides by mass spectrometry YORK UNIVERSITY 2002-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP GLO1 102/4885PTGS1 2882/4885GSTK1 2251/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD GLO1 1188/4885PTGS1 3440/4885GSTK1 1642/4885
US-20250255993-A1 STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND USES THEREOF RCN1, RABL6, QPCT GLO1 801/4885PTGS1 4381/4885GSTK1 1887/4885
US-20250228958-A1 TSP1 INHIBITOR ANXA11, SERPINC1, NPR1 GLO1 3966/4885PTGS1 1185/4885GSTK1 4732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.