Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152555 | 0.84 | MAPT (0.52) | LPAR3CAMK2ACYP1A2ALDH1A1MAPT | |
| SCHEMBL9152543 | 0.84 | MAPT (0.52) | LPAR3CAMK2ACYP1A2ALDH1A1MAPT | |
| SCHEMBL6175515 | 0.82 | CAMK2A (0.68) | HSD17B10CAMK2AAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL6864121 | 0.81 | HSD17B10 (0.56) | HSD17B10CAMK2AAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL1626559 | 0.77 | CYP1A2 (0.63) | CYP1A2ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL29812478 | 0.77 | CYP1A2 (0.63) | CYP1A2ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL25386626 | 0.77 | NFE2L2 (0.55) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL30334863 | 0.77 | NFE2L2 (0.55) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL30059246 | 0.76 | LMNA (0.61) | AKR1C3AKR1C2ALDH1A1MAPTLMNA | |
| SCHEMBL515302 | 0.76 | LMNA (0.61) | AKR1C3AKR1C2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973730-B1 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6294531-B1 | AMINOALKANOLS AS BLOOD COAGULANTS | SMITHKLINE BEECHAM CORPORATION | 2001-09-25 | — | — | US | disclosed |
| EP-0973730-A1 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998045255-A1 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-15 | — | — | WO | disclosed |