Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.49 |
| ▸ | CA9 | Q16790 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | HPN | P05981 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866173 | 0.94 | CA12 (0.51) | CA12CA9CA1CA2MMP1 | |
| SCHEMBL7040350 | 0.91 | CA12 (0.48) | CA12CA9CA1CA2MMP1 | |
| SCHEMBL6868990 | 0.82 | ALDH1A1 (0.55) | CA12CA9CA1CA2MMP1 | |
| Diethylamine SCHEMBL22229832 | 0.73 | PTGES (0.62) | CA12CA9CA1CA2MMP1 | |
| SCHEMBL6868015 | 0.72 | PTGES (0.68) | CA12CA9CA1CA2MMP1 | |
| SCHEMBL31374599 | 0.72 | SPHK1 (0.51) | CA12CA9CA1CA2MAPT | |
| SCHEMBL27000244 | 0.71 | CA12 (0.61) | CA12CA9CA1CA2MMP1 | |
| SCHEMBL6868985 | 0.71 | CA12 (0.58) | CA12CA9CA1CA2MMP1 | |
| SCHEMBL18136593 | 0.70 | MAPT (0.48) | MMP2MMP9MMP8PLAUHPN | |
| SCHEMBL6868979 | 0.70 | CA12 (0.44) | CA12CA9CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806291-B1 | 2-(((4-HYDROXYPHENYL)CARBAMOYL)ALKYLSULFAMOYL)BENZOIC ACIDS; LIMITED HEPATOTOXIC EFFECT | THE FOUNDATION FOR THE LSU HEALTH SCIENCES CENTER | 2004-10-19 | — | — | US | disclosed |