Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 6/20 | 0.55 |
| ▸ | CA9 | Q16790 | 6/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL22229832 | 0.94 | PTGES (0.62) | PTGESCYP3A4CA12CA9CA1 | |
| SCHEMBL22073589 | 0.88 | CYP3A4 (0.60) | PTGESCYP3A4CA12CA9MEN1 | |
| SCHEMBL6868985 | 0.87 | CA12 (0.58) | PTGESCYP3A4CA12CA9CA1 | |
| SCHEMBL22027542 | 0.86 | CYP3A4 (0.63) | PTGESCYP3A4CA12CA9MEN1 | |
| SCHEMBL7040346 | 0.85 | CA12 (0.60) | PTGESCYP3A4CA12CA9CA1 | |
| SCHEMBL31087520 | 0.85 | CYP3A4 (0.57) | PTGESCYP3A4CA12CA9MEN1 | |
| SCHEMBL22073690 | 0.85 | CYP3A4 (0.57) | PTGESCYP3A4CA12CA9MEN1 | |
| SCHEMBL22073588 | 0.85 | CYP3A4 (0.67) | PTGESCYP3A4CA12CA9MEN1 | |
| SCHEMBL6865453 | 0.84 | CA12 (0.60) | PTGESCYP3A4CA12CA9CA1 | |
| SCHEMBL6866169 | 0.83 | CA12 (0.59) | PTGESCYP3A4CA12CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11529355-B2 | Compositions and methods for ameliorating pain and reducing fever | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2022-12-20 | — | — | US | disclosed |
| US-11529355-B2 | Compositions and methods for ameliorating pain and reducing fever | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2022-12-20 | — | — | US | disclosed |
| US-20210379075-A1 | COMPOSITIONS AND METHODS FOR AMELIORATING PAIN AND REDUCING FEVER | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2021-12-09 | — | — | US | disclosed |
| US-11007199-B2 | Compositions and methods for ameliorating pain and reducing fever | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2021-05-18 | — | — | US | disclosed |
| US-20200230087-A1 | COMPOSITIONS AND METHODS FOR AMELIORATING PAIN AND REDUCING FEVER | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-07-23 | — | — | US | disclosed |
| US-20200179393-A1 | COMPOSITIONS AND METHODS FOR AMELIORATING PAIN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-06-11 | — | — | US | disclosed |
| EP-1682496-B1 | ANALGESIC COMPOUNDS, THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UNIV LOUISIANA STATE (US) | 2009-04-08 | — | — | EP | disclosed |
| US-6806291-B1 | 2-(((4-HYDROXYPHENYL)CARBAMOYL)ALKYLSULFAMOYL)BENZOIC ACIDS; LIMITED HEPATOTOXIC EFFECT | THE FOUNDATION FOR THE LSU HEALTH SCIENCES CENTER | 2004-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210379075-A1 | COMPOSITIONS AND METHODS FOR AMELIORATING PAIN AND REDUCING FEVER | MPO, ACHE, CAT | PTGES 19/4885CYP3A4 1694/4885CA12 358/4885 |
| US-11529355-B2 | Compositions and methods for ameliorating pain and reducing fever | MPO, ACHE, CAT | PTGES 19/4885CYP3A4 1694/4885CA12 358/4885 |
| US-20200230087-A1 | COMPOSITIONS AND METHODS FOR AMELIORATING PAIN AND REDUCING FEVER | MPO, ACHE, CAT | PTGES 19/4885CYP3A4 1694/4885CA12 358/4885 |
| US-20200179393-A1 | COMPOSITIONS AND METHODS FOR AMELIORATING PAIN | ACHE, MPO, MMP8 | PTGES 38/4885CYP3A4 4236/4885CA12 381/4885 |
| US-11007199-B2 | Compositions and methods for ameliorating pain and reducing fever | MPO, ACHE, CAT | PTGES 19/4885CYP3A4 1694/4885CA12 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.