Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040350 | 0.84 | CA12 (0.48) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL6865455 | 0.82 | CA12 (0.49) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL6866173 | 0.81 | CA12 (0.51) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL26212920 | 0.76 | CA1 (0.64) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL6868015 | 0.74 | PTGES (0.68) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL27000244 | 0.73 | CA12 (0.61) | ALDH1A1HSD17B10CA1CA2MMP1 | |
| SCHEMBL6868985 | 0.72 | CA12 (0.58) | ALDH1A1CA1CA2MMP1MMP2 | |
| Diethylamine SCHEMBL22229832 | 0.72 | PTGES (0.62) | ALDH1A1CA1CA2MMP1MMP2 | |
| SCHEMBL6868006 | 0.72 | MTOR (0.46) | ALDH1A1L3MBTL1CA1CA2MMP1 | |
| SCHEMBL6868979 | 0.72 | CA12 (0.44) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806291-B1 | 2-(((4-HYDROXYPHENYL)CARBAMOYL)ALKYLSULFAMOYL)BENZOIC ACIDS; LIMITED HEPATOTOXIC EFFECT | THE FOUNDATION FOR THE LSU HEALTH SCIENCES CENTER | 2004-10-19 | — | — | US | disclosed |