Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.68 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | IAPP | P10997 | 4/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531687 | 1.00 | TAAR1 (0.68) | TAAR1HMGB1IAPPHTR2CRECQL | |
| Hydrochloric Acid SCHEMBL10880379 | 0.98 | TAAR1 (0.65) | TAAR1HMGB1IAPPHTR2CRECQL | |
| SCHEMBL633288 | 0.87 | TAAR1 (0.52) | TAAR1HMGB1IAPPRECQLTDP1 | |
| SCHEMBL18469204 | 0.82 | TAAR1 (0.68) | TAAR1HMGB1HTR2CRECQLTDP1 | |
| SCHEMBL1427697 | 0.81 | TAAR1 (1.00) | TAAR1HTR2CRECQLTDP1MEN1 | |
| SCHEMBL10414030 | 0.81 | IAPP (0.59) | IAPPRECQLTDP1ALOX15HSD17B10 | |
| SCHEMBL366656 | 0.81 | ADAMTS4 (0.52) | TAAR1IAPPRECQLTDP1ALOX15 | |
| SCHEMBL29769908 | 0.81 | TAAR1 (1.00) | TAAR1HTR2CRECQLTDP1MEN1 | |
| SCHEMBL8680504 | 0.80 | TAAR1 (0.65) | TAAR1HMGB1HTR2CRECQLTDP1 | |
| SCHEMBL10762848 | 0.80 | HMGB1 (0.56) | TAAR1HMGB1HTR2CRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107298873-B | Preparation method of melanin | 江南大学 | 2020-01-07 | — | — | CN | disclosed |
| CN-110436524-A | A kind of zinc molybdate carbon composite nano ball and preparation method thereof | UNIV SHAANXI SCIENCE & TECH | 2019-11-12 | — | — | CN | disclosed |
| CN-109749115-A | Hydrophilic polyurethane carrier and preparation method and application thereof | 中国石油化工股份有限公司 | 2019-05-14 | — | — | CN | disclosed |
| US-9560848-B2 | Method and compositions for biofouling deterrence | CLEMSON UNIVERSITY (US) | 2017-02-07 | — | — | US | disclosed |
| US-20140243286-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| US-20130252848-A1 | CELLOMICS SYSTEM | KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY (JP) | 2013-09-26 | — | — | US | disclosed |
| WO-2013033270-A2 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| CN-102774984-A | Method for treating high-concentration ammonia nitrogen in chemical industrial wastewater | UNIV CHANGZHOU | 2012-11-14 | — | — | CN | disclosed |
| EP-2479203-A1 | AROMATIC POLYESTER | Muroran Institute of Technology (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20120172570-A1 | AROMATIC POLYESTER | NITTA CORPORATION | 2012-07-05 | — | — | US | disclosed |
| EP-1626278-A2 | Cellomics system | OnChip Cellomics Consortium (JP) | 2006-02-15 | — | — | EP | disclosed |
| US-6998405-B2 | Parkinson's and Huntington's disease; psychoses, impotence, renal or heart failure, schizophrenia | H. LUNDBECK A/S (DK) | 2006-02-14 | — | — | US | disclosed |
| EP-1274411-B1 | PHENYLETHYLAMINES AND CONDENSED RINGS VARIANTS AS PRODRUGS OF CATECHOLAMINES, AND THEIR USE | LUNDBECK & CO AS H (DK) | 2005-07-27 | — | — | EP | disclosed |
| JP-2004323866-A | METHOD FOR MANUFACTURING NICKEL POWDER, AND NICKEL POWDER | MURATA MFG CO LTD | 2004-11-18 | — | — | JP | disclosed |
| US-20040138281-A1 | Phenylethylamines and condensed rings variants as prodrugs of catecholamines, and their use | AXON BIOCHEMICALS B.V. (NL) | 2004-07-15 | — | — | US | disclosed |
| US-6683087-B2 | TREATMENT OF PARKINSON'S DISEASE, PSYCHOSES, HUNTINGTON'S DISEASE, IMPOTENCE, RENAL FAILURE, HEART FAILURE OR HYPERTENSION | AXON BIOCHEMICALS B.V. (NL) | 2004-01-27 | — | — | US | disclosed |
| US-20030087948-A1 | Phenylethylamines and condensed rings variants as prodrugs of catecholamines, and their use | H. LUNDBECK A/S (DK) | 2003-05-08 | — | — | US | disclosed |
| EP-1274411-A1 | PHENYLETHYLAMINES AND CONDENSED RINGS VARIANTS AS PRODRUGS OF CATECHOLAMINES, AND THEIR USE | Axon Biochemicals B.V. (NL) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001078713-A1 | PHENYLETHYLAMINES AND CONDENSED RINGS VARIANTS AS PRODRUGS OF CATECHOLAMINES, AND THEIR USE | AXON BIOCHEMICALS B.V. (NL) | 2001-10-25 | — | — | WO | disclosed |
| US-4313956-A | Novel sypathomimetic amine prodrugs | INTERX RESEARCH CORP. (US) | 1982-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138281-A1 | Phenylethylamines and condensed rings variants as prodrugs of catecholamines, and their use | ADRA1D, ABCE1, ADRA1B | TAAR1 169/4885HMGB1 3647/4885IAPP 569/4885 |
| US-20140243286-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | BRDT, BRD4, BRD1 | TAAR1 2423/4885HMGB1 418/4885IAPP 3074/4885 |
| US-20030087948-A1 | Phenylethylamines and condensed rings variants as prodrugs of catecholamines, and their use | ADRA1D, ABCE1, ADRA1B | TAAR1 165/4885HMGB1 3693/4885IAPP 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.