Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | ICMT | O60725 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865449 | 0.97 | CA12 (0.47) | CA12CA9ESR1ESR2MTOR | |
| SCHEMBL7040342 | 0.92 | CA12 (0.45) | CA12CA9ESR1MTORCA1 | |
| SCHEMBL6868979 | 0.88 | CA12 (0.44) | CA12CA9MTORCA1CA2 | |
| SCHEMBL6868006 | 0.79 | MTOR (0.46) | CA12CA9MTORALDH1A1CA1 | |
| SCHEMBL3454762 | 0.71 | CA12 (0.55) | CA12CA9CA1CA2MEN1 | |
| SCHEMBL6866173 | 0.71 | CA12 (0.51) | CA12CA9ALDH1A1MAPK1CA1 | |
| SCHEMBL6865455 | 0.68 | CA12 (0.49) | CA12CA9ALDH1A1MAPK1CA1 | |
| SCHEMBL8982627 | 0.68 | CA12 (0.61) | CA12CA9ALDH1A1CA1CA2 | |
| SCHEMBL6868990 | 0.68 | ALDH1A1 (0.55) | CA12CA9ALDH1A1CA1CA2 | |
| SCHEMBL7040350 | 0.68 | CA12 (0.48) | CA12CA9ALDH1A1MAPK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806291-B1 | 2-(((4-HYDROXYPHENYL)CARBAMOYL)ALKYLSULFAMOYL)BENZOIC ACIDS; LIMITED HEPATOTOXIC EFFECT | THE FOUNDATION FOR THE LSU HEALTH SCIENCES CENTER | 2004-10-19 | — | — | US | disclosed |