Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868979 | 0.84 | CA12 (0.44) | MTORNPY5RCA1CA2MMP1 | |
| SCHEMBL6865449 | 0.80 | CA12 (0.47) | MTORCA1LMNAALDH1A1CA12 | |
| SCHEMBL6866165 | 0.79 | CA12 (0.48) | MTORCA1CA2LMNAALDH1A1 | |
| SCHEMBL28119618 | 0.76 | KCNJ6 (0.53) | MTORBCAT2LMNAALDH1A1HPGD | |
| SCHEMBL29385278 | 0.73 | MCL1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5515234 | 0.73 | MCL1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6868990 | 0.72 | ALDH1A1 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6868015 | 0.71 | PTGES (0.68) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL7934335 | 0.71 | F2 (0.40) | CA1CA2MMP1MMP2MMP9 | |
| Diethylamine SCHEMBL22229832 | 0.69 | PTGES (0.62) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806291-B1 | 2-(((4-HYDROXYPHENYL)CARBAMOYL)ALKYLSULFAMOYL)BENZOIC ACIDS; LIMITED HEPATOTOXIC EFFECT | THE FOUNDATION FOR THE LSU HEALTH SCIENCES CENTER | 2004-10-19 | — | — | US | disclosed |