Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866948 | 1.00 | OPRM1 (0.54) | OPRM1OPRL1LMNAKMT2AHTT | |
| SCHEMBL6878138 | 0.91 | MCHR1 (0.48) | OPRM1OPRL1LMNAKMT2AHTT | |
| SCHEMBL6878146 | 0.91 | MCHR1 (0.48) | OPRM1OPRL1LMNAKMT2AHTT | |
| SCHEMBL6876199 | 0.89 | MCHR1 (0.47) | OPRM1OPRL1LMNAKMT2AHTT | |
| SCHEMBL6876191 | 0.89 | MCHR1 (0.47) | OPRM1OPRL1LMNAKMT2AHTT | |
| SCHEMBL6873072 | 0.89 | MCHR1 (0.45) | OPRM1OPRL1LMNAKMT2AHTT | |
| SCHEMBL6873067 | 0.89 | MCHR1 (0.45) | OPRM1OPRL1LMNAKMT2AHTT | |
| SCHEMBL6459479 | 0.87 | SIGMAR1 (0.52) | KMT2AHTTMCHR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6459469 | 0.87 | SIGMAR1 (0.52) | KMT2AHTTMCHR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6866938 | 0.84 | MCHR1 (0.55) | LMNAKMT2AMCHR1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |