Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | TP53 | P04637 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | USP2 | O75604 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876191 | 1.00 | MCHR1 (0.47) | MCHR1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL6878414 | 0.90 | TP53 (0.44) | MCHR1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL6878418 | 0.90 | TP53 (0.44) | MCHR1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL6866941 | 0.89 | OPRM1 (0.54) | MCHR1LMNATP53KMT2AUSP2 | |
| SCHEMBL6866948 | 0.89 | OPRM1 (0.54) | MCHR1LMNATP53KMT2AUSP2 | |
| SCHEMBL6878138 | 0.88 | MCHR1 (0.48) | MCHR1LMNAKMT2AKDM4EOPRM1 | |
| SCHEMBL6878146 | 0.88 | MCHR1 (0.48) | MCHR1LMNAKMT2AKDM4EOPRM1 | |
| SCHEMBL6874473 | 0.85 | MCHR1 (0.50) | MCHR1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL6877772 | 0.85 | MCHR1 (0.50) | MCHR1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL6874467 | 0.85 | MCHR1 (0.50) | MCHR1LMNATP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |