Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878146 | 1.00 | MCHR1 (0.48) | MCHR1ADRA2AOPRM1OPRL1LMNA | |
| SCHEMBL6866941 | 0.91 | OPRM1 (0.54) | MCHR1ADRA2AOPRM1OPRL1LMNA | |
| SCHEMBL6866948 | 0.91 | OPRM1 (0.54) | MCHR1ADRA2AOPRM1OPRL1LMNA | |
| SCHEMBL6875524 | 0.90 | MCHR1 (0.49) | MCHR1ADRA2ALMNASIGMAR1SLC6A4 | |
| SCHEMBL6466930 | 0.90 | MCHR1 (0.49) | MCHR1ADRA2ALMNASIGMAR1SLC6A4 | |
| SCHEMBL6876191 | 0.88 | MCHR1 (0.47) | MCHR1OPRM1OPRL1LMNAHTT | |
| SCHEMBL6876199 | 0.88 | MCHR1 (0.47) | MCHR1OPRM1OPRL1LMNAHTT | |
| SCHEMBL13793703 | 0.84 | MCHR1 (0.66) | MCHR1ADRA2AOPRM1OPRL1NPY5R | |
| Trifluoroacetic Acid SCHEMBL6461543 | 0.82 | LMNA (0.45) | MCHR1ADRA2AOPRM1OPRL1LMNA | |
| SCHEMBL6873072 | 0.80 | MCHR1 (0.45) | MCHR1ADRA2AOPRM1OPRL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |