Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4296343 | 0.82 | RECQL (0.58) | RECQLMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL2831553 | 0.78 | MAPT (0.40) | RECQLMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL6869652 | 0.74 | ALDH1A1 (0.53) | RECQLMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL3200271 | 0.74 | MAPT (0.38) | RECQLMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL6867220 | 0.74 | MAPT (0.47) | RECQLMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL7238315 | 0.74 | MAPT (0.43) | RECQLMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL2828429 | 0.74 | GABRA2 (0.45) | RECQLMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL8822967 | 0.73 | GABRA2 (0.40) | GABRA2GABRB2GABRB3LMNA | |
| SCHEMBL3219619 | 0.73 | MAPT (0.40) | RECQLMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL2829188 | 0.73 | MAPT (0.42) | RECQLMAPTHPGDALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056601-A1 | Control agent containing N-Substituted indole derivative for acarian parasitic on animal | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2010-03-04 | — | — | US | claimed |
| US-20090270459-A1 | Flea control agent containing N-Substituted indole derivative | TANABE SATOSHI | 2009-10-29 | — | — | US | claimed |
| US-20070197578-A1 | Control agent containing n-substituted indole derivative for acarian parasitic on animal | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-08-23 | — | — | US | claimed |
| US-20070135491-A1 | Flea control agent containing n-substitute indole derivative | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-06-14 | — | — | US | claimed |
| US-20100056601-A1 | Control agent containing N-Substituted indole derivative for acarian parasitic on animal | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2010-03-04 | — | — | US | disclosed |
| US-20100056601-A1 | Control agent containing N-Substituted indole derivative for acarian parasitic on animal | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2010-03-04 | — | — | US | disclosed |
| US-20090270459-A1 | Flea control agent containing N-Substituted indole derivative | TANABE SATOSHI | 2009-10-29 | — | — | US | disclosed |
| US-20090270459-A1 | Flea control agent containing N-Substituted indole derivative | TANABE SATOSHI | 2009-10-29 | — | — | US | disclosed |
| US-20070197578-A1 | Control agent containing n-substituted indole derivative for acarian parasitic on animal | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-08-23 | — | — | US | disclosed |
| US-20070135491-A1 | Flea control agent containing n-substitute indole derivative | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-06-14 | — | — | US | disclosed |
| US-20070135491-A1 | Flea control agent containing n-substitute indole derivative | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-06-14 | — | — | US | disclosed |
| WO-2005102055-A1 | CONTROL AGENT CONTAINING N-SUBSTITUTED INDOLE DERIVATIVE FOR ACARIAN PARASITIC ON ANIMAL | NIPPON KAYAKU KABUSHIKIKAISHA (JP) | 2005-11-03 | — | — | WO | disclosed |
| WO-2005102050-A1 | FLEA CONTROL AGENT CONTAINING N-SUBSTITUTED INDOLE DERIVATIVE | NIPPON KAYAKU KABUSHIKIKAISHA (JP) | 2005-11-03 | — | — | WO | disclosed |
| JP-2003146809-A | MITE CONTROLLING AGENT COMPRISING N=SUBSTITUTED INDOLE DERIVATIVE | NIPPON KAYAKU CO LTD | 2003-05-21 | — | — | JP | disclosed |
| JP-2003146810-A | FLEA CONTROLLING AGENT COMPRISING N-SUBSTITUTED INDOLE DERIVATIVE | NIPPON KAYAKU CO LTD | 2003-05-21 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197578-A1 | Control agent containing n-substituted indole derivative for acarian parasitic on animal | IDO1, INMT, IDO2 | RECQL 3747/4885MAPT 2778/4885HPGD 3425/4885 |
| US-20070135491-A1 | Flea control agent containing n-substitute indole derivative | IDO1, INMT, IDO2 | RECQL 4230/4885MAPT 4381/4885HPGD 3606/4885 |
| US-20090270459-A1 | Flea control agent containing N-Substituted indole derivative | IDO1, IDO2, DDT | RECQL 4312/4885MAPT 4341/4885HPGD 3938/4885 |
| US-20100056601-A1 | Control agent containing N-Substituted indole derivative for acarian parasitic on animal | IDO1, INMT, IDO2 | RECQL 4111/4885MAPT 2488/4885HPGD 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.