Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873737 | 0.91 | L3MBTL1 (0.43) | KDM4EHPGDALDH1A1TSHRLMNA | |
| SCHEMBL6869924 | 0.88 | CHRM4 (0.47) | KDM4EPOLBHPGDALDH1A1GAA | |
| SCHEMBL6870516 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1GAALMNAKMT2A | |
| SCHEMBL6871432 | 0.83 | ADORA2A (0.40) | HPGDALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL6870625 | 0.82 | MAPK10 (0.45) | KDM4EALDH1A1MAPTGAALMNA | |
| SCHEMBL6867623 | 0.81 | F2 (0.43) | KDM4EHPGDALDH1A1GAALMNA | |
| SCHEMBL6872431 | 0.80 | HDAC3 (0.40) | KDM4EEGLN2HPGDALDH1A1MAPT | |
| SCHEMBL6863441 | 0.79 | HPGD (0.45) | KDM4EPOLBHPGDALDH1A1TSHR | |
| SCHEMBL6872923 | 0.79 | ADORA2A (0.46) | EGLN2ALDH1A1TSHRMAPTGAA | |
| SCHEMBL6872215 | 0.78 | EGLN2 (0.42) | KDM4EEGLN2ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |