Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23587983 | 0.82 | EGLN1 (0.41) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL17848826 | 0.82 | FFAR3 (0.41) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL3415684 | 0.81 | EGLN1 (0.39) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL26978208 | 0.79 | AKR1B1 (0.43) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL23505946 | 0.78 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL22343513 | 0.78 | EGLN1 (0.37) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL13785296 | 0.78 | EGLN1 (0.43) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL16883005 | 0.78 | EGLN1 (0.43) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL18747596 | 0.77 | EGLN1 (0.46) | EGLN1KDM6BKDM5CPHF8KDM2A | |
| SCHEMBL6860245 | 0.77 | EGLN1 (0.46) | EGLN1KDM6BKDM5CPHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110281921-A1 | NOVEL ANTI-BIOFILM AGENTS | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2011-11-17 | — | — | US | disclosed |
| WO-2010058402-A1 | NOVEL ANTI-BIOFILM AGENTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2010-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281921-A1 | NOVEL ANTI-BIOFILM AGENTS | PYCARD, DNM2, MMP8 | EGLN1 372/4885KDM6B 2679/4885KDM5C 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.