SCHEMBL686789

SCHEMBL686789

O=[PH](O)Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
AKR1B1 P15121 1/20 0.44
TSHR P16473 1/20 0.43
MAOB P27338 1/20 0.42
CALM1 P0DP23 1/20 0.41
KEAP1 Q14145 1/20 0.41
F2 P00734 1/20 0.41
PLG P00747 1/20 0.41
ELANE P08246 1/20 0.41
CTSG P08311 1/20 0.41
CMA1 P23946 1/20 0.41
CTRC Q99895 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
THRB P10828 1/20 0.39
IDO1 P14902 1/20 0.39
EPHX2 P34913 1/20 0.39
HDAC8 Q9BY41 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL17670041 0.97 CES2 (0.42) CES2CES1AKR1B1TSHRMAOB
Hydrochloric Acid SCHEMBL10915156 0.97 CES2 (0.42) CES2CES1AKR1B1TSHRMAOB
Biphenyl SCHEMBL1967082 0.93 LMNA (0.43) CES2CES1AKR1B1TSHRMAOB
Butane SCHEMBL5417876 0.91 TP53 (0.42) CES2CES1AKR1B1TSHRCYP2C19
SCHEMBL21993580 0.86 LMNA (0.52) TSHRIDO1MEN1KMT2AHPGD
SCHEMBL21112093 0.86 NOS1 (0.31) CES2CES1
SCHEMBL26604910 0.83
SCHEMBL26604944 0.83
SCHEMBL23881858 0.81 LTA4H (0.57) TSHR
SCHEMBL16353245 0.81 KMT2A (0.44) TSHRTDP1CYP1A2CYP2C19HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 553 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777192-A Phosphorus-boron type Schiff base derivative flame retardant, and preparation method and application thereof 北京工商大学 2024-03-29 CN claimed
CN-117777193-A Phosphorus-containing Schiff base derivative flame retardant, and preparation method and application thereof 北京工商大学 2024-03-29 CN claimed
WO-2023138015-A1 ALUMINUM DIETHYLPHOSPHINATE FLAME RETARDANT AND PREPARATION METHOD THEREFOR 兰州瑞朴科技有限公司 2023-07-27 WO claimed
CN-114478624-A Telomer of aluminum diethylphosphinate and preparation method thereof 兰州瑞朴科技有限公司 2022-05-13 CN claimed
CN-114181250-A Alkenyl phosphine compound and preparation method thereof 中国石油化工股份有限公司 2022-03-15 CN claimed
CN-112591806-A Method for recovering and regenerating anode active material of waste lithium ion battery 中南大学 2021-04-02 CN claimed
EP-2907512-A1 Inhibitors of MMP-12 as antiviral Agents COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-08-19 EP claimed
US-8383702-B2 Composite materials having improved thermal performance SAINT-GOBAIN CERAMICS & PLASTICS, INC. (US) 2013-02-26 US claimed
EP-1354906-B1 Polyamide resin MITSUBISHI GAS CHEMICAL CO (JP) 2012-12-05 EP claimed
US-20120053317-A1 BIAXIALLY ORIENTED POLYESTER FILM FOR SOLAR CELLS TEIJIN DUPONT FILMS JAPAN LIMITED (JP) 2012-03-01 US claimed
EP-2423248-A1 BIAXIALLY STRETCHED POLYESTER FILM FOR SOLAR BATTERY Teijin Dupont Films Japan Limited (JP) 2012-02-29 EP claimed
EP-1607400-A2 Salts of dialkylphosphinic acids, process for their preparation and their use Clariant GmbH (DE) 2005-12-21 EP claimed
US-6841651-B2 Polyamide resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-01-11 US claimed
US-20030199667-A1 Polyamide resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-10-23 US claimed
EP-1354906-A1 Polyamide resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-10-22 EP claimed
US-5424441-A Nootropic, antiepileptic agents CIBA-GEIGY CORPORATION (US) 1995-06-13 US claimed
US-5245005-A Amine end groups, phosphinic acid catalyst MONSANTO COMPANY (US) 1993-09-14 US claimed
EP-0185132-B1 NOVEL ETHYL BENZYLPHOSPHINATE DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND THEIR USE AS CALCIUM ANTAGONIST KANEBO, LTD. (JP) 1988-08-10 EP claimed
US-4637885-A LUBE OIL, AMINE OR QUATERNARY AMMONIUM SALT OF PHOSPHORIC ACID KAO CORPORATION (JP) 1987-01-20 US claimed
US-4626367-A Water-soluble metal-working lubricant composition KAO CORPORATION (JP) 1986-12-02 US claimed