Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19112150 | 0.83 | LOXL2 (0.57) | LOXL2ADRB2PDPK1CYP2A6PTGDR2 | |
| SCHEMBL533419 | 0.77 | LOXL2 (0.67) | LOXL2ADRB2PDPK1CYP2A6PTGDR2 | |
| SCHEMBL19112147 | 0.76 | ADRB2 (0.49) | ADRB2CYP2A6 | |
| SCHEMBL10130841 | 0.76 | LOXL2 (0.61) | LOXL2ADRB2PDPK1CYP2A6ABL1 | |
| SCHEMBL14210017 | 0.75 | LOXL2 (0.56) | LOXL2ADRB2PDPK1PTGDR2ABL1 | |
| SCHEMBL2291509 | 0.74 | LOXL2 (0.51) | LOXL2ADRB2PDPK1PTGDR2SLC6A4 | |
| SCHEMBL2291507 | 0.74 | LOXL2 (0.51) | LOXL2ADRB2PDPK1PTGDR2SLC6A4 | |
| SCHEMBL722198 | 0.74 | PDPK1 (0.77) | LOXL2ADRB2PDPK1CYP2A6PTGDR2 | |
| SCHEMBL6868143 | 0.74 | LTA4H (0.53) | FFAR1HDAC1HDAC2HDAC6LTA4H | |
| SCHEMBL6852601 | 0.73 | LOXL2 (0.67) | LOXL2ADRB2PDPK1CYP2A6PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023864-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2011-03-03 | — | — | WO | disclosed |