Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31030093 | 1.00 | BRD4 (0.38) | BRD4MAPTMMELMNACA12 | |
| SCHEMBL2322722 | 1.00 | BRD4 (0.38) | BRD4MAPTMMELMNACA12 | |
| SCHEMBL16223981 | 1.00 | BRD4 (0.38) | BRD4MAPTMMELMNACA12 | |
| SCHEMBL31030092 | 1.00 | BRD4 (0.38) | BRD4MAPTMMELMNACA12 | |
| SCHEMBL2322732 | 1.00 | BRD4 (0.38) | BRD4MAPTMMELMNACA12 | |
| SCHEMBL2329044 | 1.00 | BRD4 (0.38) | BRD4MAPTMMELMNACA12 | |
| SCHEMBL22129282 | 1.00 | BRD4 (0.38) | BRD4MAPTMMELMNACA12 | |
| SCHEMBL22426199 | 1.00 | BRD4 (0.38) | BRD4MAPTMMELMNACA12 | |
| SCHEMBL22231243 | 1.00 | BRD4 (0.38) | BRD4MAPTMMELMNACA12 | |
| SCHEMBL5012986 | 0.91 | ACE (0.43) | BRD4MAPTMMEACETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119595805-A | Method for detecting related substances of brivaracetam oral liquid | 海南卫康制药(潜山)有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119178812-A | Method for detecting brivaracetam related substances | 宜昌人福药业有限责任公司 | 2024-12-24 | — | — | CN | claimed |
| EP-4036244-B1 | ENZYMATIC PROCESS FOR THE PREPARATION OF (2S)-2-[(4R)-2-OXO-4-PROPYL-PYRROLIDIN-1-YL]BUTYRIC ACID AND ITS CONVERSION INTO BRIVARACETAM | DIVIS LABORATORIES LTD (IN) | 2023-10-11 | — | — | EP | claimed |
| WO-2023100110-A1 | PROCESS FOR PREPARING BRIVARACETAM | MACFARLAN SMITH LIMITED (GB) | 2023-06-08 | — | — | WO | claimed |
| CN-111579706-B | Method for detecting hydrolysis impurities of brivaracetam | 宜宾市南溪区红光制药有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115806519-A | Method for splitting intermediate of brivaracetam and application of intermediate | 浙江普洛家园药业有限公司 | 2023-03-17 | — | — | CN | claimed |
| US-20220241242-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF (2S)-2-[(4R)-2-OXO-4-PROPYL-PYRROLIDIN-1-YL]BUTYRIC ACID AND ITS CONVERSION INTO BRIVARACETAM | DIVIS LABORATORIES LTD (IN) | 2022-08-04 | — | — | US | claimed |
| US-11400074-B1 | Enzymatic process for the preparation of (2S)-2-[(4R)-2-oxo-4-propyl-pyrrolidin-1-yl]butyric acid and its conversion into brivaracetam | DIVI'S LABORATORIES LTD. (IN) | 2022-08-02 | — | — | US | claimed |
| CN-111579706-A | Detection method of impurities in hydrolysis of brivaracetam | 宜宾市南溪区红光制药有限公司 | 2020-08-25 | — | — | CN | claimed |
| CN-119595805-A | Method for detecting related substances of brivaracetam oral liquid | 海南卫康制药(潜山)有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-119178812-A | Method for detecting brivaracetam related substances | 宜昌人福药业有限责任公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-119178812-A | Method for detecting brivaracetam related substances | 宜昌人福药业有限责任公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-118986873-A | Brivarenical tablets preparation of the tam solution method and brivaracetam solution | 海南卫康制药(潜山)有限公司 | 2024-11-22 | — | — | CN | disclosed |
| US-20240270689-A1 | PROCESS FOR PRODUCING BRIVARACETAM AND INTERMEDIATES THEREOF | CARNITECH LLC | 2024-08-15 | — | — | US | disclosed |
| WO-2016191435-A1 | PROCESSES TO PRODUCE BRIVARACETAM | WANG PENG (US) | 2016-12-01 | — | — | WO | disclosed |
| US-8338621-B2 | Process for the preparation of 2-oxo-1-pyrrolidine derivatives | UCB S.A. (BE) | 2012-12-25 | — | — | US | disclosed |
| US-8338621-B2 | Process for the preparation of 2-oxo-1-pyrrolidine derivatives | UCB S.A. (BE) | 2012-12-25 | — | — | US | disclosed |
| EP-1806339-B1 | Process for the preparation of 2-oxo-1-pyrrolidine derivatives | UCB PHARMA SA (BE) | 2011-08-17 | — | — | EP | disclosed |
| US-20080009638-A1 | PROCESS FOR THE PREPARATION OF 2-OXO-1-PYRROLIDINE DERIVATIVES | UCB S.A. (BE) | 2008-01-10 | — | — | US | disclosed |
| US-20080009638-A1 | PROCESS FOR THE PREPARATION OF 2-OXO-1-PYRROLIDINE DERIVATIVES | UCB S.A. (BE) | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009638-A1 | PROCESS FOR THE PREPARATION OF 2-OXO-1-PYRROLIDINE DERIVATIVES | CYP2F1, CYP3A5, SULT1E1 | BRD4 631/4885MAPT 1791/4885MME 4138/4885 |
| US-11400074-B1 | Enzymatic process for the preparation of (2S)-2-[(4R)-2-oxo-4-propyl-pyrrolidin-1-yl]butyric acid and its conversion into brivaracetam | BPGM, GABRP, GABRB1 | BRD4 72/4885MAPT 1265/4885MME 2775/4885 |
| US-20220241242-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF (2S)-2-[(4R)-2-OXO-4-PROPYL-PYRROLIDIN-1-YL]BUTYRIC ACID AND ITS CONVERSION INTO BRIVARACETAM | BPGM, GABRP, GABRB1 | BRD4 73/4885MAPT 1223/4885MME 2762/4885 |
| US-20240270689-A1 | PROCESS FOR PRODUCING BRIVARACETAM AND INTERMEDIATES THEREOF | POR, BLVRB, CYP2B6 | BRD4 647/4885MAPT 4108/4885MME 3593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.