Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | PTPRA | P18433 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19112147 | 0.81 | ADRB2 (0.49) | ADRB2CLK4AOC3CYP2A6PPARG | |
| SCHEMBL19112149 | 0.78 | ADRB2 (0.53) | ADRB2CLK4AOC3CYP2A6PPARG | |
| SCHEMBL10130811 | 0.77 | ADRB2 (0.57) | ADRB2CLK4MAPK1 | |
| SCHEMBL14122679 | 0.76 | ADRB2 (0.52) | ADRB2PPARGHDAC4PTPRA | |
| SCHEMBL19112028 | 0.76 | SRR (0.49) | PPARG | |
| SCHEMBL11834703 | 0.75 | MMP12 (0.49) | ADRB2PPARG | |
| SCHEMBL533651 | 0.74 | ADRB2 (0.63) | ADRB2CLK4AOC3CYP2A6 | |
| SCHEMBL19112150 | 0.74 | LOXL2 (0.57) | ADRB2CYP2A6HDAC4 | |
| SCHEMBL31369650 | 0.73 | SLC7A5 (0.61) | ADRB2 | |
| SCHEMBL26966009 | 0.73 | SLC7A5 (0.61) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470514-B1 | PSEUDO-DIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-07-12 | — | — | EP | disclosed |
| WO-2011023864-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2011-03-03 | — | — | WO | disclosed |