Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | BMP1 | P13497 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP10 | P09238 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19111957 | 0.83 | NOD1 (0.46) | NOD1MMP12MMP2MMP8SIRT5 | |
| SCHEMBL24024002 | 0.83 | MMP12 (0.48) | NOD1MMP12MMP2MMP8HPGDS | |
| SCHEMBL11978793 | 0.83 | MMP12 (0.48) | NOD1MMP12MMP2MMP8HPGDS | |
| SCHEMBL13908025 | 0.81 | NOD1 (0.49) | NOD1MMP12MMP2MMP8HPGDS | |
| SCHEMBL19724151 | 0.81 | NOD1 (0.49) | NOD1MMP12MMP2MMP8HPGDS | |
| SCHEMBL21243004 | 0.81 | SIRT5 (0.45) | NOD1MMP12MMP2MMP8SIRT5 | |
| SCHEMBL19033489 | 0.81 | NOD1 (0.44) | NOD1MMP12MMP2MMP8SIRT5 | |
| SCHEMBL14753916 | 0.80 | SIRT5 (0.47) | NOD1SIRT5HPGDSBMP1FOLH1 | |
| SCHEMBL17793208 | 0.80 | DPP4 (0.53) | NOD1SIRT5HPGDSBMP1FOLH1 | |
| SCHEMBL17951006 | 0.80 | SIRT5 (0.60) | NOD1SIRT5HPGDSBMP1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023864-A1 | PSEUDODIPEPTIDES AS MMP INHIBITORS | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2011-03-03 | — | — | WO | disclosed |