Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 4/20 | 0.43 |
| ▸ | BMP1 | P13497 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | GNPAT | O15228 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP10 | P09238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17948382 | 0.91 | MMP12 (0.48) | NOD1MMP12MMP2MMP8MMP13 | |
| SCHEMBL22827992 | 0.85 | CA2 (0.41) | NOD1MMP12BMP1MMP2MMP8 | |
| SCHEMBL6869880 | 0.81 | NOD1 (0.49) | NOD1MMP12BMP1MMP2MMP8 | |
| SCHEMBL11978793 | 0.80 | MMP12 (0.48) | NOD1MMP12MMP2MMP8MMP13 | |
| SCHEMBL24024002 | 0.80 | MMP12 (0.48) | NOD1MMP12MMP2MMP8MMP13 | |
| SCHEMBL13908025 | 0.79 | NOD1 (0.49) | NOD1MMP12MMP2MMP8MMP13 | |
| SCHEMBL19724151 | 0.79 | NOD1 (0.49) | NOD1MMP12MMP2MMP8MMP13 | |
| SCHEMBL19111957 | 0.78 | NOD1 (0.46) | NOD1MMP12BMP1MMP2MMP8 | |
| SCHEMBL30463270 | 0.78 | DPP4 (0.45) | NOD1BMP1HPGDSPTPN1FOLH1 | |
| SCHEMBL22489300 | 0.77 | HPGDS (0.46) | NOD1MMP12BMP1MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170182176-A1 | POLYMERS HAVING THERAPEUTICALLY ACTIVE AGENTS CONJUGATED THERETO, PROCESSES OF PREPARING SAME AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-06-29 | — | — | US | disclosed |
| US-9687562-B2 | Polymers having therapeutically active agents conjugated thereto, processes of preparing same and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170182176-A1 | POLYMERS HAVING THERAPEUTICALLY ACTIVE AGENTS CONJUGATED THERETO, PROCESSES OF PREPARING SAME AND USES THEREOF | CD47, VCAM1, CD44 | NOD1 1586/4885MMP12 413/4885BMP1 2624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.