SCHEMBL687102

SCHEMBL687102

Cc1n[nH]c(N)c1-c1nc2cc(CO)ccc2s1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ILK Q13418 19/20 0.72
HSD17B10 Q99714 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL687517 0.90 ILK (0.72) ILK
SCHEMBL686934 0.83 ILK (0.70) ILK
SCHEMBL686453 0.81 ILK (0.70) ILK
SCHEMBL686489 0.79 ILK (0.72) ILK
SCHEMBL687608 0.78 ILK (0.55) ILK
SCHEMBL686809 0.78 ILK (0.72) ILK
SCHEMBL686899 0.78 ILK (0.57) ILK
SCHEMBL686473 0.77 ILK (0.76) ILK
SCHEMBL687029 0.77 ILK (0.49) ILK
SCHEMBL687560 0.76 ILK (0.76) ILK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9434720-B2 Pyrazolylbenzothiazole derivatives and their use as therapeutic agents DIRMIRA (CANADA), INC. (US) 2016-09-06 US claimed
US-20140350009-A1 PYRAZOLYLBENZOTHIAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS DERMIRA (CANADA), INC. (US) 2014-11-27 US claimed
EP-1542997-B1 PYRAZOLYLBENZOTHIAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS DERMIRA CANADA INC (CA) 2012-02-29 EP claimed
US-7847101-B2 such as (4-Benzothiazol-2-yl-1H-pyrazol-3-yl)-[2-(1H-imidazol-4-yl)-ethyl]-amine, used in the treatment of disorders associated with hyperproliferation and tissue remodelling or repair, inflammation, cell migration and invasion, and renal diseases, or as protein kinase inhibitors Valocor Therapeutics, Inc. (CA) 2010-12-07 US claimed
US-20060247210-A1 such as (4-Benzothiazol-2-yl-1H-pyrazol-3-yl)-[2-(1H-imidazol-4-yl)-ethyl]-amine, used in the treatment of disorders associated with hyperproliferation and tissue remodelling or repair, inflammation, cell migration and invasion, and renal diseases, or as protein kinase inhibitors QLT INC. (CA) 2006-11-02 US claimed
EP-0553887-A2 Catalysts and epoxy resin composition containing the same THE DOW CHEMICAL COMPANY (US) 1993-08-04 EP claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
EP-3668936-B1 TWO-COMPONENT ROOM TEMPERATURE CURABLE TOUGHENED EPOXY ADHESIVES DDP SPECIALTY ELECTRONIC MATERIALS US LLC (US) 2024-07-17 EP disclosed
EP-3844202-B1 EPOXY COMPOSITE FORMULATION DOW GLOBAL TECHNOLOGIES LLC (US) 2024-06-19 EP disclosed
WO-2024015165-A1 ADHESIVE COMPOSITION DDP SPECIALTY ELECTRONIC MATERIALS US, LLC (US) 2024-01-18 WO disclosed
WO-2024015163-A1 ADHESIVE COMPOSITION DDP SPECIALTY ELECTRONIC MATERIALS US, LLC (US) 2024-01-18 WO disclosed
EP-3405510-B2 ONE-COMPONENT EPOXY-MODIFIED POLYURETHANE AND/OR POLYUREA ADHESIVES HAVING HIGH ELONGATION AND EXCELLENT THERMAL STABILITY, AND ASSEMBLY PROCESSES USING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-07 EP disclosed
EP-4116385-A1 AQUEOUS DUAL-COMPONENT WOODWARE SEALING PRIMER Guangdong Huarun Paints Co. Ltd. (CN) 2023-01-11 EP disclosed
US-20060247210-A1 such as (4-Benzothiazol-2-yl-1H-pyrazol-3-yl)-[2-(1H-imidazol-4-yl)-ethyl]-amine, used in the treatment of disorders associated with hyperproliferation and tissue remodelling or repair, inflammation, cell migration and invasion, and renal diseases, or as protein kinase inhibitors QLT INC. (CA) 2006-11-02 US disclosed
US-6194024-B1 CONNECTING TWO CIRCUIT CARRIERS; FILLING HOLE WITH SOLDER SPHERE INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-02-27 US disclosed
EP-0729484-B1 CURE INHIBITED EPOXY RESIN COMPOSITIONS AND LAMINATES PREPARED FROM THE COMPOSITIONS DOW CHEMICAL CO (US) 2000-03-01 EP disclosed
US-5571593-A CIRCUIT CARRIERS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-11-05 US disclosed
US-5503937-A MIXTURE OF A COMPOUND HAVING MORE THAN ONE EPOXY GROUP, A DIHYDRIC PHENOLIC COMPOUND AND A LATENT CATALYST COMPRISING A SALT OF AN N-HETEROCYCLIC COMPOUND AND AN ACID HAVING A STRONG NUCLEOPHILIC ANION; COATINGS/MOLDINGS; STORAGE THE DOW CHEMICAL COMPANY (US) 1996-04-02 US disclosed
EP-0553887-A2 Catalysts and epoxy resin composition containing the same THE DOW CHEMICAL COMPANY (US) 1993-08-04 EP disclosed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247210-A1 such as (4-Benzothiazol-2-yl-1H-pyrazol-3-yl)-[2-(1H-imidazol-4-yl)-ethyl]-amine, used in the treatment of disorders associated with hyperproliferation and tissue remodelling or repair, inflammation, cell migration and invasion, and renal diseases, or as protein kinase inhibitors TST, PTK2, PTK2B ILK 2153/4885HSD17B10 2968/4885
US-20140350009-A1 PYRAZOLYLBENZOTHIAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS COXFA4L2, TYR, XDH ILK 4705/4885HSD17B10 1535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.