Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 11/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6872616 | 1.00 | ALDH1A1 (0.53) | ALDH1A1PTPN11RARBMAPTMEN1 | |
| SCHEMBL6872710 | 0.99 | ALDH1A1 (0.51) | ALDH1A1PTPN11RARBMAPTMEN1 | |
| SCHEMBL6872614 | 0.96 | ALDH1A1 (0.54) | ALDH1A1PTPN11RARBMAPTMEN1 | |
| SCHEMBL6872019 | 0.96 | ALDH1A1 (0.54) | ALDH1A1PTPN11RARBMAPTMEN1 | |
| SCHEMBL6875660 | 0.95 | ALDH1A1 (0.46) | ALDH1A1PTPN11RARBMAPTMEN1 | |
| SCHEMBL6872705 | 0.95 | ALDH1A1 (0.52) | ALDH1A1PTPN11RARBTP53TSHR | |
| SCHEMBL389088 | 0.93 | ALDH1A1 (0.56) | ALDH1A1PTPN11RARBMAPTMEN1 | |
| SCHEMBL6388182 | 0.92 | ALDH1A1 (0.46) | ALDH1A1PTPN11RARBMAPTMEN1 | |
| SCHEMBL6390329 | 0.92 | ALDH1A1 (0.46) | ALDH1A1PTPN11RARBMAPTMEN1 | |
| SCHEMBL6875656 | 0.92 | ALDH1A1 (0.47) | ALDH1A1PTPN11RARBMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821581-B2 | ESTER DERIVATIVES OF TEREPHTHALIC ACID ESTERS; HAVE A HELICAL TWISTING POWER OF AT LEAST 9; HELICAL PITCH INDUCED DECREASES IN LENGTH WITH AN INCREASE IN TEMPERATURE. | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-11-23 | — | — | US | disclosed |
| US-20030124268-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO., INC. | 2003-07-03 | — | — | US | disclosed |
| EP-1270542-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030124268-A1 | Optically active compound and liquid crystal composition containing the compound | CRY1, CRY2, PNP | ALDH1A1 4498/4885PTPN11 1015/4885RARB 4280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.