Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | RARB | P10826 | 9/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875660 | 0.96 | ALDH1A1 (0.46) | ALDH1A1PTPN11RARBTSHRMAPT | |
| SCHEMBL6872705 | 0.96 | ALDH1A1 (0.52) | ALDH1A1PTPN11RARBTSHRTP53 | |
| SCHEMBL6872019 | 0.95 | ALDH1A1 (0.54) | ALDH1A1PTPN11RARBTSHRMAPT | |
| SCHEMBL6872614 | 0.95 | ALDH1A1 (0.54) | ALDH1A1PTPN11RARBTSHRMAPT | |
| SCHEMBL6872710 | 0.93 | ALDH1A1 (0.51) | ALDH1A1PTPN11RARBTSHRMAPT | |
| SCHEMBL6872616 | 0.92 | ALDH1A1 (0.53) | ALDH1A1PTPN11RARBTSHRMAPT | |
| SCHEMBL6872020 | 0.92 | ALDH1A1 (0.53) | ALDH1A1PTPN11RARBTSHRMAPT | |
| SCHEMBL6390327 | 0.90 | ALDH1A1 (0.46) | ALDH1A1PTPN11RARBTSHRMAPT | |
| SCHEMBL6388176 | 0.90 | ALDH1A1 (0.46) | ALDH1A1PTPN11RARBTSHRMAPT | |
| SCHEMBL7780458 | 0.89 | PTPN11 (0.58) | ALDH1A1PTPN11RARBTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821581-B2 | ESTER DERIVATIVES OF TEREPHTHALIC ACID ESTERS; HAVE A HELICAL TWISTING POWER OF AT LEAST 9; HELICAL PITCH INDUCED DECREASES IN LENGTH WITH AN INCREASE IN TEMPERATURE. | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2004-11-23 | — | — | US | disclosed |
| US-20030124268-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL CO., INC. | 2003-07-03 | — | — | US | disclosed |
| EP-1270542-A1 | Optically active compound and liquid crystal composition containing the compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030124268-A1 | Optically active compound and liquid crystal composition containing the compound | CRY1, CRY2, PNP | ALDH1A1 4498/4885PTPN11 1015/4885RARB 4280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.