Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.34 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705899 | 0.76 | ALDH1A1 (0.54) | HCAR2KDM4EP4HTMNAPRTP4HA1 | |
| SCHEMBL24787182 | 0.76 | CA12 (0.36) | HCAR2KDM4EP4HTMNAPRTP4HA1 | |
| SCHEMBL10328694 | 0.74 | HCAR2 (0.41) | HCAR2KDM4EP4HTMNAPRTP4HA1 | |
| SCHEMBL361106 | 0.74 | KDM4E (0.52) | HCAR2KDM4EP4HTMNAPRTP4HA1 | |
| SCHEMBL286703 | 0.74 | HCAR2 (0.41) | HCAR2KDM4EP4HTMNAPRTP4HA1 | |
| SCHEMBL20929049 | 0.74 | HCAR2 (0.34) | HCAR2KDM4EP4HTMNAPRTP4HA1 | |
| SCHEMBL3695695 | 0.74 | GABRP (0.41) | HCAR2KDM4EP4HTMNAPRTP4HA1 | |
| SCHEMBL9852803 | 0.74 | APLNR (0.45) | HCAR2KDM4EALDH1A1HSD17B10ALOX15 | |
| SCHEMBL18520707 | 0.74 | TPMT (0.39) | HCAR2KDM4EP4HTMNAPRTP4HA1 | |
| SCHEMBL30526873 | 0.72 | NPC1 (0.43) | KDM4EP4HTMP4HA1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091410-A1 | TRPV4 ANTAGONISTS | GLAXOS SMITHKLINE LLC (US) | 2011-07-28 | — | — | WO | disclosed |