SCHEMBL20929049

SCHEMBL20929049

O=C(O)c1ncc(S)cn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.34
KDM4E B2RXH2 4/20 0.34
P4HTM Q9NXG6 3/20 0.34
NAPRT Q6XQN6 3/20 0.34
P4HA1 P13674 2/20 0.34
MIF P14174 1/20 0.33
ALDH1A1 P00352 4/20 0.32
HSD17B10 Q99714 3/20 0.32
ALOX15 P16050 2/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
GABRB2 P47870 1/20 0.32
GABRA4 P48169 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3705899 0.76 ALDH1A1 (0.54) HCAR2KDM4EP4HTMNAPRTP4HA1
SCHEMBL24787182 0.76 CA12 (0.36) HCAR2KDM4EP4HTMNAPRTP4HA1
SCHEMBL10328694 0.74 HCAR2 (0.41) HCAR2KDM4EP4HTMNAPRTP4HA1
SCHEMBL18520707 0.74 TPMT (0.39) HCAR2KDM4EP4HTMNAPRTP4HA1
SCHEMBL286703 0.74 HCAR2 (0.41) HCAR2KDM4EP4HTMNAPRTP4HA1
SCHEMBL3695695 0.74 GABRP (0.41) HCAR2KDM4EP4HTMNAPRTP4HA1
SCHEMBL6873117 0.74 HCAR2 (0.37) HCAR2KDM4EP4HTMNAPRTP4HA1
SCHEMBL9852803 0.74 APLNR (0.45) HCAR2KDM4EALDH1A1HSD17B10ALOX15
SCHEMBL361106 0.74 KDM4E (0.52) HCAR2KDM4EP4HTMNAPRTP4HA1
SCHEMBL20929050 0.73 P4HA1 (0.31) HCAR2KDM4EP4HTMNAPRTP4HA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11022880-B2 Chemically amplified positive-type photosensitive resin composition, photosensitive dry film, method of manufacturing photosensitive dry film, method of manufacturing patterned resist film, method of manufacturing substrate with template, method of manufacturing plated article, and mercapto compound TOKYO OHKA KOGYO CO., LTD. (JP) 2021-06-01 US disclosed
US-20190121233-A1 CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PATTERNED RESIST FILM, METHOD OF MANUFACTURING SUBSTRATE WITH TEMPLATE, METHOD OF MANUFACTURING PLATED ARTICLE, AND MERCAPTO COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2019-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190121233-A1 CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PHOTOSENSITIVE DRY FILM, METHOD OF MANUFACTURING PATTERNED RESIST FILM, METHOD OF MANUFACTURING SUBSTRATE WITH TEMPLATE, METHOD OF MANUFACTURING PLATED ARTICLE, AND MERCAPTO COMPOUND CUTA, POLR1C, ASIC1 HCAR2 3020/4885KDM4E 2101/4885P4HTM 1981/4885
US-11022880-B2 Chemically amplified positive-type photosensitive resin composition, photosensitive dry film, method of manufacturing photosensitive dry film, method of manufacturing patterned resist film, method of manufacturing substrate with template, method of manufacturing plated article, and mercapto compound CUTA, POLR1C, ASIC1 HCAR2 3020/4885KDM4E 2101/4885P4HTM 1981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.