Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883425 | 0.86 | ROCK2 (0.45) | RAB9ALMNAMAPTALDH1A1ROCK2 | |
| SCHEMBL8063431 | 0.83 | PPARG (0.53) | RAB9ALMNAMAPTALDH1A1ROCK2 | |
| SCHEMBL6875823 | 0.82 | RAB9A (0.50) | RAB9ALMNAMAPTALDH1A1ROCK2 | |
| SCHEMBL7136553 | 0.79 | LMNA (0.50) | RAB9ALMNAMAPTALDH1A1ROCK2 | |
| SCHEMBL7145773 | 0.79 | ROCK2 (0.53) | RAB9ALMNAMAPTALDH1A1ROCK2 | |
| SCHEMBL7147820 | 0.79 | LMNA (0.48) | RAB9ALMNAMAPTALDH1A1ROCK2 | |
| SCHEMBL7146575 | 0.78 | ROCK2 (0.50) | RAB9ALMNAMAPTALDH1A1ROCK2 | |
| SCHEMBL27490613 | 0.78 | ROCK2 (0.50) | RAB9ALMNAMAPTALDH1A1ROCK2 | |
| SCHEMBL18595010 | 0.78 | ROCK2 (0.59) | RAB9AROCK2ROCK1NPC1SMN1; SMN2 | |
| SCHEMBL7145903 | 0.78 | ROCK2 (0.44) | RAB9ALMNAMAPTALDH1A1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123283-B1 | THIAZOLE-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2004-05-06 | — | — | EP | claimed |