Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938502 | 0.73 | LMNA (0.46) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL582333 | 0.70 | HSD17B10 (0.41) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL687395 | 0.69 | ALDH1A1 (0.39) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL123650 | 0.69 | CD44 (0.49) | LMNAKDM4E | |
| SCHEMBL2535555 | 0.68 | ANPEP (0.55) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL29811500 | 0.68 | ANPEP (0.55) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL31274510 | 0.68 | ANPEP (0.55) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL37705 | 0.68 | PNMT (0.39) | HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL7354925 | 0.66 | ANPEP (0.53) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL54652 | 0.66 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242471-B1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-29 | — | — | EP | claimed |
| US-6515155-B1 | Group 4 metal complexes of the constrained geometry type, catalysts derived therefrom and polymerization processes using the same, characterized by a nitrogen containing aliphatic or cycloaliphatic moiety that is substituted with one or more | DOW GLOBAL TECHNOLOGIES INC. | 2003-02-04 | — | — | US | claimed |
| US-20030004286-A1 | Alkaryl-substituted Group 4 metal complexes, catalysts and olefin polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2003-01-02 | — | — | US | claimed |
| US-20020165329-A1 | Heat-resistant group 4 metal metallecenes having a nitrogen with aliphatic or cycloaliphatic moiety substituted with aryl group(s)and a silane bridge; high-molecular weight ethylene-alpha olefin copolymers; high concentration of comonomer | KLOSIN JERZY (US) | 2002-11-07 | — | — | US | claimed |
| EP-1253158-A1 | Substituted group 4 metal complexes, catalysts and olefin polymerization process | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-10-30 | — | — | EP | claimed |
| EP-1242471-B1 | SUBSTITUTED GROUP 4 METAL COMPLEXES, CATALYSTS AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-29 | — | — | EP | disclosed |
| US-6825295-B2 | COORDINATION POLYMERIZATION CATALYST | DOW GLOBAL TECHNOLOGIES INC. | 2004-11-30 | — | — | US | disclosed |
| US-6515155-B1 | Group 4 metal complexes of the constrained geometry type, catalysts derived therefrom and polymerization processes using the same, characterized by a nitrogen containing aliphatic or cycloaliphatic moiety that is substituted with one or more | DOW GLOBAL TECHNOLOGIES INC. | 2003-02-04 | — | — | US | disclosed |
| US-20030004286-A1 | Alkaryl-substituted Group 4 metal complexes, catalysts and olefin polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2003-01-02 | — | — | US | disclosed |
| US-20020165329-A1 | Heat-resistant group 4 metal metallecenes having a nitrogen with aliphatic or cycloaliphatic moiety substituted with aryl group(s)and a silane bridge; high-molecular weight ethylene-alpha olefin copolymers; high concentration of comonomer | KLOSIN JERZY (US) | 2002-11-07 | — | — | US | disclosed |
| EP-1253158-A1 | Substituted group 4 metal complexes, catalysts and olefin polymerization process | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165329-A1 | Heat-resistant group 4 metal metallecenes having a nitrogen with aliphatic or cycloaliphatic moiety substituted with aryl group(s)and a silane bridge; high-molecular weight ethylene-alpha olefin copolymers; high concentration of comonomer | B2M, WEE2, WASF2 | ALDH1A1 2123/4885HSD17B10 894/4885CYP2A6 1018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.