Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 10/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874188 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MCHR1HTTRAB9AADRA2A | |
| SCHEMBL6878501 | 0.92 | RAB9A (0.56) | ALDH1A1MCHR1RAB9AADRA2ASMN1; SMN2 | |
| SCHEMBL6878491 | 0.92 | RAB9A (0.56) | ALDH1A1MCHR1RAB9AADRA2ASMN1; SMN2 | |
| SCHEMBL6866381 | 0.89 | HSD11B1 (0.48) | ALDH1A1MCHR1RAB9AADRA2AKMT2A | |
| SCHEMBL6866386 | 0.89 | HSD11B1 (0.48) | ALDH1A1MCHR1RAB9AADRA2AKMT2A | |
| SCHEMBL6873253 | 0.87 | HSD11B1 (0.58) | ALDH1A1MCHR1RAB9AADRA2AKMT2A | |
| SCHEMBL6873257 | 0.87 | HSD11B1 (0.58) | ALDH1A1MCHR1RAB9AADRA2AKMT2A | |
| SCHEMBL13793261 | 0.84 | MCHR1 (0.69) | ALDH1A1MCHR1HTTRAB9AADRA2A | |
| SCHEMBL6455456 | 0.83 | MCHR1 (0.47) | ALDH1A1MCHR1RAB9AADRA2AKMT2A | |
| SCHEMBL6455463 | 0.83 | MCHR1 (0.47) | ALDH1A1MCHR1RAB9AADRA2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |