Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14864751 | 0.80 | NAMPT (0.42) | NAMPTSPRALDH1A1HSD17B10TSHR | |
| SCHEMBL8235837 | 0.80 | TSHR (0.42) | SPRALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL4692525 | 0.79 | MCL1 (0.47) | NAMPTSPRALDH1A1HSD17B10TSHR | |
| SCHEMBL19069559 | 0.79 | MEN1 (0.40) | NAMPTSPRALDH1A1TSHRFAAH | |
| SCHEMBL13014696 | 0.78 | ALDH1A1 (0.42) | NAMPTALDH1A1HSD17B10TSHRCASP1 | |
| SCHEMBL23677003 | 0.78 | ALDH1A1 (0.47) | NAMPTSPRALDH1A1HSD17B10TSHR | |
| SCHEMBL14307931 | 0.78 | RAB9A (0.44) | NAMPTSPRALDH1A1HSD17B10HPGD | |
| SCHEMBL7828830 | 0.77 | MEN1 (0.58) | ALDH1A1TSHRFAAHMEN1KMT2A | |
| SCHEMBL13296412 | 0.76 | FAAH (0.55) | NAMPTALDH1A1TSHRHPGDFAAH | |
| SCHEMBL10073128 | 0.76 | ALDH1A1 (0.43) | NAMPTSPRALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |