Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.36 |
| ▸ | MERTK | Q12866 | 2/20 | 0.36 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874272 | 1.00 | EPHX1 (0.46) | EPHX1EPHX2KDM4EPKMMAPT | |
| SCHEMBL6867882 | 0.97 | KDM4E (0.46) | EPHX1EPHX2KDM4EPKMMAPT | |
| SCHEMBL6867886 | 0.97 | KDM4E (0.46) | EPHX1EPHX2KDM4EPKMMAPT | |
| SCHEMBL6875441 | 0.90 | ALDH1A1 (0.45) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL6875449 | 0.90 | ALDH1A1 (0.45) | MAPTNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL6879546 | 0.87 | EPHX1 (0.56) | EPHX1EPHX2KDM4EPKMMAPT | |
| SCHEMBL6879538 | 0.87 | EPHX1 (0.56) | EPHX1EPHX2KDM4EPKMMAPT | |
| SCHEMBL6879246 | 0.86 | RAB9A (0.44) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6879250 | 0.86 | RAB9A (0.44) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6878845 | 0.86 | SMN1; SMN2 (0.52) | MAPTNPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |