Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.41 |
| ▸ | CTSS | P25774 | 10/20 | 0.41 |
| ▸ | CTSB | P07858 | 6/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5523062 | 0.93 | CTSS (0.49) | CTSKCTSSCTSBCTSLKDM4E | |
| SCHEMBL5517701 | 0.88 | CTSS (0.40) | CTSKCTSSCTSBCTSLKDM4E | |
| SCHEMBL5523888 | 0.88 | CTSS (0.52) | CTSKCTSSCTSBCTSLALDH1A1 | |
| SCHEMBL5523068 | 0.88 | CTSK (0.40) | CTSKCTSSCTSBCTSL | |
| SCHEMBL5526366 | 0.88 | L3MBTL1 (0.46) | CTSKCTSSCTSBCTSLKDM4E | |
| SCHEMBL5529717 | 0.86 | CTSS (0.46) | CTSKCTSSCTSBCTSLKDM4E | |
| SCHEMBL5525439 | 0.83 | USP30 (0.50) | KDM4EALDH1A1 | |
| SCHEMBL5530343 | 0.81 | POLB (0.50) | CTSLKDM4EALDH1A1LMNA | |
| SCHEMBL5526866 | 0.80 | CTSL (0.45) | CTSKCTSSCTSBCTSL | |
| SCHEMBL5523008 | 0.79 | CTSL (0.44) | CTSKCTSSCTSBCTSLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |