Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6462999 | 0.88 | MCHR1 (0.46) | SLC2A1ADRA2AMCHR1ALDH1A1KDM4E | |
| SCHEMBL6875398 | 0.88 | MCHR1 (0.46) | SLC2A1ADRA2AMCHR1ALDH1A1KDM4E | |
| SCHEMBL6867944 | 0.83 | ADRA2A (0.42) | ADRA2AMCHR1TACR1ALDH1A1KDM4E | |
| SCHEMBL6867978 | 0.83 | ADRA2A (0.42) | ADRA2AMCHR1TACR1ALDH1A1KDM4E | |
| SCHEMBL6877439 | 0.82 | ACHE (0.42) | ADRA2AMCHR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL6869183 | 0.82 | KDM1A (0.44) | SLC2A1ADRA2AMCHR1KDM4EMAPT | |
| SCHEMBL6877433 | 0.82 | ACHE (0.42) | ADRA2AMCHR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL6869175 | 0.82 | KDM1A (0.44) | SLC2A1ADRA2AMCHR1KDM4EMAPT | |
| SCHEMBL6879311 | 0.81 | MAPK8 (0.43) | ADRA2AMCHR1CDK1CDK4CCND1 | |
| SCHEMBL6879316 | 0.81 | MAPK8 (0.43) | ADRA2AMCHR1CDK1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |