Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30682408 | 0.87 | ALDH1A1 (0.47) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL10420297 | 0.79 | S100B (0.50) | ALDH1A1CYP3A4TDP1ADKNTSR1 | |
| SCHEMBL12674298 | 0.78 | USP1 (0.35) | GAAALDH1A1CYP3A4HTTTDP1 | |
| SCHEMBL12666655 | 0.78 | BRAF (0.32) | CYP3A4LMNAHTTNTSR1 | |
| SCHEMBL10208072 | 0.77 | ALDH1A1 (0.55) | GAAALDH1A1CYP3A4MEN1MAPT | |
| SCHEMBL18562081 | 0.76 | BRAF (0.41) | ALDH1A1MEN1MAPTKMT2AHTT | |
| SCHEMBL3039281 | 0.75 | TDP1 (0.46) | ALDH1A1CYP3A4MAPTL3MBTL1TDP1 | |
| SCHEMBL6872660 | 0.75 | SMN1; SMN2 (0.48) | GAAALDH1A1CYP3A4MEN1MAPT | |
| SCHEMBL12288117 | 0.75 | MAPT (0.48) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL5713569 | 0.75 | KMT2A (0.37) | GAAALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713499-B2 | ADENOSINE RECEPTOR AGONIST | HOFFMAN-LA ROCHE INC. | 2004-03-30 | — | — | US | disclosed |
| US-20030153566-A1 | 7-Amino-benzothiazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153566-A1 | 7-Amino-benzothiazole derivatives | ADORA1, ADORA2A, ADORA3 | GAA 2652/4885ALDH1A1 308/4885CYP3A4 954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.