Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3778349 | 0.82 | EPHX1 (0.66) | EPHX1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL14423982 | 0.82 | EPHX1 (0.79) | EPHX1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL4902274 | 0.82 | EPHX1 (0.66) | EPHX1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL6873118 | 0.81 | EPHX1 (0.58) | EPHX1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL14470502 | 0.79 | PRMT3 (0.74) | EPHX1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL14424451 | 0.79 | EPHX1 (0.89) | EPHX1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL12196199 | 0.79 | EPHX1 (1.00) | EPHX1RAB9ANPC1MAPTCYP1A2 | |
| SCHEMBL9547503 | 0.79 | RAB9A (0.89) | EPHX1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL13480580 | 0.78 | EPHX1 (0.69) | EPHX1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL14424481 | 0.78 | EPHX1 (0.97) | EPHX1RAB9ANPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |