Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 12/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 11/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875943 | 1.00 | EHMT2 (0.39) | EHMT2MCHR1ADRA2APYGLHTR1A | |
| SCHEMBL6879134 | 0.87 | EHMT2 (0.38) | EHMT2MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6879138 | 0.87 | EHMT2 (0.38) | EHMT2MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6868774 | 0.86 | MCHR1 (0.37) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL6868783 | 0.86 | MCHR1 (0.37) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL6460216 | 0.82 | EHMT2 (0.44) | EHMT2MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6460210 | 0.82 | EHMT2 (0.44) | EHMT2MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL27632573 | 0.82 | DRD2 (0.39) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL27632572 | 0.82 | DRD2 (0.39) | MCHR1ADRA2AHTR1AADRA1AHRH1 | |
| SCHEMBL7046594 | 0.81 | ALDH1A1 (0.50) | MCHR1ADRA2AHTR1AADRA1AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |