Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875977 | 1.00 | ALOX12 (0.56) | ALOX12MAPTMCHR1ADRA2ANPC1 | |
| SCHEMBL6879414 | 0.90 | MCHR1 (0.46) | ALOX12MAPTMCHR1ADRA2ALMNA | |
| SCHEMBL6879419 | 0.90 | MCHR1 (0.46) | ALOX12MAPTMCHR1ADRA2ALMNA | |
| SCHEMBL6875974 | 0.90 | LMNA (0.54) | ALOX12MAPTMCHR1ADRA2ANPC1 | |
| SCHEMBL6875979 | 0.90 | LMNA (0.54) | ALOX12MAPTMCHR1ADRA2ANPC1 | |
| SCHEMBL6875063 | 0.90 | MCHR1 (0.47) | ALOX12MAPTMCHR1ADRA2ALMNA | |
| SCHEMBL6875068 | 0.90 | MCHR1 (0.47) | ALOX12MAPTMCHR1ADRA2ALMNA | |
| SCHEMBL6873184 | 0.90 | ADRA2A (0.46) | ALOX12MAPTMCHR1ADRA2ALMNA | |
| SCHEMBL6873178 | 0.90 | ADRA2A (0.46) | ALOX12MAPTMCHR1ADRA2ALMNA | |
| SCHEMBL7044566 | 0.89 | BCHE (0.46) | ALOX12MAPTMCHR1ADRA2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |