Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MIF | P14174 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4531507 | 0.87 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1TP53TYR | |
| SCHEMBL1884508 | 0.86 | ALDH1A1 (0.73) | ALDH1A1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL5210059 | 0.85 | KMT2A (0.62) | RAB9ANPC1KMT2AMEN1CA1 | |
| Urea SCHEMBL307661 | 0.84 | KMT2A (0.60) | RAB9ANPC1KMT2AMEN1CA1 | |
| SCHEMBL5361111 | 0.83 | CA1 (0.63) | ALDH1A1RAB9ANPC1POLBKMT2A | |
| SCHEMBL5695334 | 0.83 | RAB9A (0.71) | ALDH1A1RAB9ANPC1POLBKMT2A | |
| SCHEMBL1185244 | 0.82 | KMT2A (0.58) | RAB9ANPC1KMT2AMEN1CA1 | |
| SCHEMBL11517562 | 0.82 | CA1 (0.71) | ALDH1A1RAB9ANPC1POLBKMT2A | |
| SCHEMBL983433 | 0.81 | ALDH1A1 (1.00) | ALDH1A1RAB9ANPC1POLBKMT2A | |
| SCHEMBL23932088 | 0.81 | KMT2A (0.66) | ALDH1A1RAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232467-B | Thiazole aminobenzoic acid derivative and application thereof | 南华大学 | 2022-11-25 | — | — | CN | claimed |
| CN-109320473-B | Thiazolylaminobenzamide acetic acid derivatives and uses thereof | 南华大学 | 2022-11-22 | — | — | CN | claimed |
| CN-109456279-B | Thiazolylaminobenzamide acetate derivatives and uses thereof | 南华大学 | 2022-11-22 | — | — | CN | claimed |
| CN-111909111-B | 5-alkyl thiazolamine derivative and application thereof in depression resistance | 深圳市第二人民医院(深圳市转化医学研究院) | 2022-07-01 | — | — | CN | claimed |
| CN-111875558-B | Thiazolidine derivative and application thereof in depression resistance | 深圳市第二人民医院(深圳市转化医学研究院) | 2022-07-01 | — | — | CN | claimed |
| CN-113493219-A | Tin dioxide quantum dot material, preparation method thereof and photoelectric device | 香港理工大学深圳研究院 | 2021-10-12 | — | — | CN | claimed |
| CN-111909111-A | 5-alkyl thiazolamine derivative and application thereof in depression resistance | 深圳市第二人民医院(深圳市转化医学研究院) | 2020-11-10 | — | — | CN | claimed |
| CN-111875558-A | Thiazolidine derivative and application thereof in depression resistance | 深圳市第二人民医院(深圳市转化医学研究院) | 2020-11-03 | — | — | CN | claimed |
| US-20230263167-A1 | METHOD OF PREPARING A BISMUTH SULFIDE PARTICLE CONTAINING ANTIBACTERIAL COMPOSITION | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2023-08-24 | — | — | US | disclosed |
| US-11700855-B2 | Method for preventing or reducing growth of a microorganism on a surface | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2023-07-18 | — | — | US | disclosed |
| US-11530180-B2 | Alpha-5 beta-1 inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-20 | — | — | US | disclosed |
| US-11530180-B2 | Alpha-5 beta-1 inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-20 | — | — | US | disclosed |
| CN-109232467-B | Thiazole aminobenzoic acid derivative and application thereof | 南华大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-109456279-B | Thiazolylaminobenzamide acetate derivatives and uses thereof | 南华大学 | 2022-11-22 | — | — | CN | disclosed |
| WO-1997036859-A1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | disclosed |
| WO-1997036860-A1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | disclosed |
| WO-1997036862-A1 | META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS | G.D. SEARLE & CO. (US) | 1997-10-09 | — | — | WO | disclosed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | disclosed |
| US-5602277-A | Substituted benzene derivatives useful as neuraminidase inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| WO-1996030329-A1 | SUBSTITUTED BENZENE DERIVATIVES USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INCORPORATED (US) | 1996-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11530180-B2 | Alpha-5 beta-1 inhibitors | SCN5A, PSMA5, API5 | ALDH1A1 227/4885RAB9A 2227/4885NPC1 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.