SCHEMBL1884508

SCHEMBL1884508

CC(=O)c1cccc(NC(N)=S)c1

nearest known ligand 0.73

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.73
NPC1 O15118 6/20 0.65
RAB9A P51151 6/20 0.65
SMN1; SMN2 Q16637 6/20 0.65
HPGD P15428 5/20 0.65
ALOX12 P18054 2/20 0.65
KMT2A Q03164 4/20 0.63
MEN1 O00255 3/20 0.63
CYP1A2 P05177 1/20 0.61
GAA P10253 2/20 0.60
LMNA P02545 4/20 0.60
TDP1 Q9NUW8 1/20 0.60
STAT1 P42224 1/20 0.60
MAPT P10636 1/20 0.60
ATM Q13315 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28879978 0.89 ALDH1A1 (0.72) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL4531507 0.87 ALDH1A1 (0.71) ALDH1A1KMT2AMEN1CYP1A2
SCHEMBL687614 0.86 ALDH1A1 (0.69) ALDH1A1NPC1RAB9ASMN1; SMN2ALOX12
SCHEMBL4795890 0.85 KMT2A (0.66) ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL5456725 0.85 ALDH1A1 (0.83) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL983433 0.85 ALDH1A1 (1.00) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL5459330 0.84 ALDH1A1 (0.62) ALDH1A1RAB9AKMT2AMEN1CYP1A2
SCHEMBL29654057 0.84 ALDH1A1 (0.62) ALDH1A1RAB9AKMT2AMEN1CYP1A2
SCHEMBL6930688 0.82 KMT2A (0.62) ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL6816592 0.81 GAA (0.72) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069632-B Corrosion inhibition epoxy resin curing agent used in low-temperature and humid environment, preparation method and application thereof 万华化学集团股份有限公司 2026-05-19 CN claimed
CN-117069632-A Corrosion inhibition epoxy resin curing agent used in low-temperature and humid environment, preparation method and application thereof 万华化学集团股份有限公司 2023-11-17 CN claimed
CN-117069632-B Corrosion inhibition epoxy resin curing agent used in low-temperature and humid environment, preparation method and application thereof 万华化学集团股份有限公司 2026-05-19 CN disclosed
CN-117069632-A Corrosion inhibition epoxy resin curing agent used in low-temperature and humid environment, preparation method and application thereof 万华化学集团股份有限公司 2023-11-17 CN disclosed
US-20230263167-A1 METHOD OF PREPARING A BISMUTH SULFIDE PARTICLE CONTAINING ANTIBACTERIAL COMPOSITION IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-08-24 US disclosed
US-11700855-B2 Method for preventing or reducing growth of a microorganism on a surface IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-07-18 US disclosed
US-20210061670-A1 METHOD FOR PREVENTING OR REDUCING GROWTH OF A MICROORGANISM ON A SURFACE IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2021-03-04 US disclosed
US-10934176-B2 Methods of degrading organic pollutants and preventing or treating microbe using Bi2S3-CdS particles IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2021-03-02 US disclosed
US-20200102228-A1 METHODS OF DEGRADING ORGANIC POLLUTANTS AND PREVENTING OR TREATING MICROBE USING Bi2S3-CdS PARTICLES IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2020-04-02 US disclosed
US-10105687-B1 Heterostructured Bi2S3—ZnS photocatalysts and methods thereof IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2018-10-23 US disclosed
CN-105755480-B Efficient acidic cleaner 江苏筑磊电子科技有限公司 2018-06-19 CN disclosed
CN-105755480-A Efficient acidic cleaner 江苏筑磊电子科技有限公司 2016-07-13 CN disclosed
US-20110105436-A1 HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE IN CANCER TREATMENT AUCKLAND UNISERVICES LIMITED (NZ) 2011-05-05 US disclosed
CN-100381429-C Thiazole derivatives HOFFMANN LA ROCHE (CH) 2008-04-16 CN disclosed
CN-101129295-A 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems HERAEUS KULZER GMBH (DE) 2008-02-27 CN disclosed
US-7253197-B2 Aminothiazole derivatives HOFFMANN-LA ROCHE INC. (US) 2007-08-07 US disclosed
CN-1675188-A Thiazole derivatives HOFFMANN LA ROCHE (CH) 2005-09-28 CN disclosed
EP-1539722-A1 THIAZOLE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2005-06-15 EP disclosed
US-20040038990-A1 Aminothiazole derivatives HOFFMANN-LA ROCHE INC. 2004-02-26 US disclosed
WO-2004014884-A1 THIAZOLE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2004-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105436-A1 HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE IN CANCER TREATMENT VHL, TP53, BECN1 ALDH1A1 1737/4885NPC1 53/4885RAB9A 508/4885
US-20040038990-A1 Aminothiazole derivatives FABP4, GPR119, ABAT ALDH1A1 42/4885NPC1 572/4885RAB9A 1476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.