Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | GRN | P28799 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL5520630 | 0.88 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1THRBATMPOLB | |
| SCHEMBL6592042 | 0.85 | CTSS (0.49) | KDM4ECTSSCTSLGRNSORT1 | |
| SCHEMBL6879172 | 0.85 | CTSS (0.49) | KDM4ECTSSCTSLGRNSORT1 | |
| SCHEMBL6874696 | 0.84 | CPB2 (0.55) | POLBCTSSCTSLGRNSORT1 | |
| SCHEMBL6876245 | 0.79 | CTSS (0.64) | CTSSSMN1; SMN2CTSLGRNSORT1 | |
| SCHEMBL7381314 | 0.78 | GRN (0.47) | CTSSCTSLGRNSORT1CPB2 | |
| SCHEMBL7381319 | 0.78 | GRN (0.47) | CTSSCTSLGRNSORT1CPB2 | |
| SCHEMBL7379020 | 0.78 | GRN (0.47) | CTSSCTSLGRNSORT1CPB2 | |
| SCHEMBL7297681 | 0.78 | CTSS (0.48) | POLBCTSSCTSLGRNSORT1 | |
| SCHEMBL7297694 | 0.78 | CTSS (0.48) | POLBCTSSCTSLGRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |