Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.66 |
| ▸ | HTR3B | O95264 | 3/20 | 0.66 |
| ▸ | HTR3A | P46098 | 3/20 | 0.66 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.66 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.66 |
| ▸ | HTR6 | P50406 | 8/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779635 | 0.98 | HTR3E (0.68) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL1641730 | 0.97 | HTR3A (0.66) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7732043 | 0.86 | HTR3A (0.61) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL14320628 | 0.83 | MAPT (0.59) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5701472 | 0.82 | ALDH1A1 (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3973132 | 0.81 | HTR3A (0.69) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL2349863 | 0.81 | HTR3A (0.69) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL31652018 | 0.81 | HTR3A (0.69) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1397389 | 0.81 | DRD2 (0.60) | HTR6DRD2CYP2C19DRD3LMNA | |
| SCHEMBL14009665 | 0.79 | HTR3E (0.68) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419178-A1 | SOMATOSTATIN ANALOGUES AND THEIR USE SOMATOSTATIN ANALOGUES BINDING TO ALL SOMATOSTATIN RECEPTOR AND THEIR USE | University of Bern (CH) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003014158-A1 | SOMATOSTATIN ANALOGUES AND THEIR USE SOMATOSTATIN ANALOGUES BINDING TO ALL SOMATOSTATIN RECEPTOR AND THEIR USE | UNIVERSITY OF BERN (CH) | 2003-02-20 | — | — | WO | disclosed |