Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5523224 | 0.88 | ALDH1A1 (0.53) | MEN1CNR1CNR2KMT2APOLB | |
| SCHEMBL6876880 | 0.73 | KDM4E (0.42) | MEN1KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL6876670 | 0.72 | GAA (0.47) | KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6064318 | 0.69 | NAMPT (0.39) | NAMPTMEN1CNR1CNR2KMT2A | |
| SCHEMBL18409626 | 0.69 | PPARG (0.57) | — | |
| SCHEMBL6742707 | 0.69 | TSHR (0.50) | MEN1KMT2APOLBALDH1A1CYP1A2 | |
| SCHEMBL5522704 | 0.68 | GLS (0.44) | NAMPTKMT2AALDH1A1 | |
| SCHEMBL6742151 | 0.68 | STS (0.47) | KDM4E | |
| SCHEMBL6876870 | 0.67 | CTSS (0.47) | POLB | |
| SCHEMBL5519770 | 0.67 | PRMT5 (0.46) | KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | disclosed |