Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877139 | 1.00 | RAB9A (0.47) | RAB9AHSD17B10MAPTALDH1A1L3MBTL1 | |
| SCHEMBL6876406 | 0.92 | MAPT (0.49) | RAB9AMAPTALDH1A1HPGDEPHX2 | |
| SCHEMBL6876402 | 0.92 | MAPT (0.49) | RAB9AMAPTALDH1A1HPGDEPHX2 | |
| SCHEMBL6876167 | 0.90 | NPC1 (0.47) | RAB9AMAPTEPHX2EPHX1NPC1 | |
| SCHEMBL6876164 | 0.90 | NPC1 (0.47) | RAB9AMAPTEPHX2EPHX1NPC1 | |
| SCHEMBL6876610 | 0.89 | EPHX2 (0.46) | RAB9AMAPTEPHX2EPHX1NPC1 | |
| SCHEMBL6876601 | 0.89 | EPHX2 (0.46) | RAB9AMAPTEPHX2EPHX1NPC1 | |
| SCHEMBL6868638 | 0.88 | EPHX2 (0.54) | RAB9AALDH1A1HPGDEPHX2EPHX1 | |
| SCHEMBL6879538 | 0.87 | EPHX1 (0.56) | RAB9AMAPTHPGDEPHX2EPHX1 | |
| SCHEMBL6879546 | 0.87 | EPHX1 (0.56) | RAB9AMAPTHPGDEPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |